Predicot 0.05% (Ophthalmic Emulsion)

5 ml drop: ৳ 180.00

Medicine Details

Category Details
Generic Difluprednate
Company Opsonin pharma ltd

Indications

  • Treatment of inflammation and pain associated with ocular surgery
  • Treatment of uveitis
  • Treatment of pseudophakic cystoid macular edema (CME)
  • Treatment of ocular surface diseases like blepharitis & corneal inflammation

Pharmacology

  • Corticosteroids inhibit inflammatory response
  • Inhibition of edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, and scar formation
  • Thought to act by induction of phospholipase A2 inhibitory proteins
  • Structurally similar to other corticosteroids

Dosage & Administration

  • Instill 1 drop into the conjunctival sac of the affected eye 4 times daily
  • Different dosage regimens for various conditions like ocular surgery, uveitis, blepharitis, and pseudophakic cystoid macular edema

Interaction

  • Specific drug interaction studies not conducted

Contraindications

  • Contraindicated in active viral diseases of cornea and conjunctiva
  • Contraindicated in mycobacterial infection of the eye and fungal diseases of ocular structures

Side Effects

  • Elevated intraocular pressure
  • Visual acuity and field defects
  • Posterior subcapsular cataract formation
  • Secondary ocular infection
  • Perforation of the globe
  • Ocular adverse reactions
  • Corneal edema, ciliary and conjunctival hyperemia, eye pain, photophobia

Pregnancy & Lactation

  • Pregnancy Category C
  • Embryotoxic and teratogenic in rabbits
  • Use during pregnancy only if potential benefit justifies potential risk to the embryo or fetus
  • Caution during nursing

Precautions & Warnings

  • Prolonged use may result in glaucoma and cataract formation
  • Caution in patients with history of herpes simplex
  • Fungal infections of the cornea
  • Do not touch dropper tip to any surface

Use in Special Populations

  • Evaluated in pediatric patients for the treatment of inflammation following cataract surgery
  • No overall differences observed between elderly and younger patients

Overdose Effects

  • Overdosage will not ordinarily cause acute problems
  • If accidentally ingested, drink fluids to dilute

Therapeutic Class

  • Ophthalmic Steroid preparations

Storage Conditions

  • Store at room temperature
  • Protect from light and freezing
  • Contents should not be used more than 1 month after first opening of the bottle

Related Brands