Emigut 8 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Ondansetron
Company Ad din pharmaceuticals ltd
Also available as

Indications

  • Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Type

Oral soluble film

Active Ingredient

Ondansetron

Chemical Formula

C18H19N3O

Mechanism of Action

Selective blocking agent of the serotonin 5-HT3 receptor type

Dosage Forms

  • 8 mg tablet/orodispersible tablet
  • 4 mg orodispersible tablet
  • Injection
  • Oral solution
  • Oral soluble film

Administration

  • Orally dissolving film designed to be applied on top of the tongue where it will dissolve within 20 seconds and then is swallowed with saliva
  • No water required for dissolution or swallowing

Interaction

Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes

Contraindications

Hypersensitivity to the drug or any of its components, Concomitant use of apomorphine

Side Effects

  • Headache
  • Constipation
  • Diarrhea
  • Rash
  • Sensation of flushing or warmth
  • Hiccups
  • Liver enzyme abnormalities
  • Anaphylaxis
  • Brochospasm
  • Tachycardia
  • Angina
  • Hypokalemia
  • Shortness of breath

Pregnancy & Lactation

  • No evidence of impaired fertility or harm to the fetus in animal studies
  • Excreted in the breast milk of rats

Precautions

  • Hypersensitivity reactions reported in patients who have exhibited hypersensitivity to other selective 5-HT3 receptor antagonists
  • Not a drug that stimulates gastric or intestinal peristalsis

Special Populations

  • Dosage Adjustment for Patients With Impaired Renal Function
  • Dosage Adjustment for Patients With Impaired Hepatic Function
  • Limited information available about dosage in pediatric patients 4 years of age or younger
  • No dosage adjustment needed in patients over the age of 65

Therapeutic Class

Anti-emetic drugs

Storage Conditions

  • Store at temperature not exceeding 30°C
  • Protect from light and moisture

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