Emigut 4 mg/5 ml (Oral Solution)
50 ml bottle: ৳ 48.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ondansetron |
| Company | Ad din pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Description
- Oral soluble film designed to be applied on top of the tongue and dissolve within 20 seconds
- Active ingredient: Emigut base, the racemic form of Emigut, and a selective blocking agent of the serotonin 5-HT3 receptor type
Mode of Action
- Potent, highly selective 5HT3 receptor-antagonist
- Precise mode of action in the control of nausea and vomiting is not fully known
- Blocks initiation of vomiting reflex by activating vagal afferents via 5HT3 receptors
Dosage
- Different dosages for adults and pediatric patients for various indications
- Dosage adjustments for different age groups and conditions
Administration
- Oral soluble film administration steps
- Does not require water to aid dissolution or swallowing
Interaction
- Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
- Inducers or inhibitors of these enzymes may change the clearance and half-life of Emigut
Contraindications
- Hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Frequently reported adverse events: headache, constipation, diarrhea
- Rare cases of anaphylaxis, bronchospasm, tachycardia, angina, etc.
- No evidence of extrapyramidal reactions
Pregnancy & Lactation
- No evidence of impaired fertility or harm to the fetus due to Ondansetron in animal studies
- Caution advised when administered to nursing women
Precautions & Warnings
- Hypersensitivity reactions reported in patients who have exhibited hypersensitivity to other selective 5-HT3 receptor antagonists
- Not a drug that stimulates gastric or intestinal peristalsis
Use in Special Populations
- Dosage adjustment for patients with impaired renal function
- Dosage adjustment for patients with impaired hepatic function
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Store at temperature not exceeding 30°C in a dry place
- Protect from light and moisture