Ivtin 12 mg (Tablet)

Title

• Ivtin Tablet

Categories

• Medicine
• Anthelmintic

Description

• Ivtin tablet is indicated for the treatment of strongyloidiasis, onchocerciasis, filariasis, scabies, and head lice. It selectively binds to glutamate-gated chloride ion channels, leading to an increase in the permeability of cell membranes to chloride ions with hyperpolarization of the nerve or muscle cell and, ultimately, death of the parasite. The recommended dosage varies based on body weight for the treatment of strongyloidiasis and onchocerciasis. It is contraindicated in patients hypersensitive to any component of the product. Various side effects and precautions are associated with its use, and caution is advised during pregnancy and lactation.

Indications

• Treatment of strongyloidiasis
• Treatment of onchocerciasis
• Treatment of filariasis
• Treatment of scabies
• Treatment of head lice

Pharmacology

• Selective binding to glutamate-gated chloride ion channels

Dosage and administration

• 2 Tablets of Ivermectin 6 mg once daily for 5 days for treatment (if COVIO positive)
• Single-dose as mentioned below to be taken on Day 1 & same dose on Day 7 for prophylaxis based on body weight
• Recommended dosage for the treatment of strongyloidiasis and onchocerciasis based on body weight
• Doses should be taken on an empty stomach with water

Interaction

• Rare reports of increased INR when co-administered with warfarin

Contraindications

• Hypersensitivity to any component of the product

Side effects

• Adverse reactions related to the treatment of strongyloidiasis, onchocerciasis, varying from body as a whole, gastrointestinal, nervous system, psychiatric, and skin

Pregnancy and lactation

• Pregnancy Category C
• Not established for use during pregnancy
• Excreted in low concentrations in human milk

Precautions and warnings

• Potential reactions such as the Mazzotti reaction and ophthalmological reactions in patients with onchocerciasis
• Caution advised when treating severe Mazzotti reactions
• Caution advised in patients heavily infected with Loa loa

Use in special populations

• Safety and effectiveness not established in pediatric patients weighing less than 15 kg
• Clinical studies did not include sufficient numbers of subjects aged 65 and over

Therapeutic class

• Anthelmintic

Storage conditions

• Store in a dry place below 30°C
• Protect from light
• Keep out of the reach of children

Related Brands

• Scabo 3 mg (Tablet) - delta-pharma-ltd