EMT MUPS 20 mg (MUPS Tablet)
Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole mups preparation |
| Company | Desh pharmaceuticals ltd |
Title
- EMT MUPS 20 mg Tablet
- EMT MUPS 40 mg Tablet
Categories
- Medicine
- Gastrointestinal
- Pharmaceuticals
Indications
- Gastro-esophageal Reflux Disease (GERD)
- Risk reduction in NSAID associated gastric ulcer
- H. pylori eradication (Triple therapy)
- Zollinger-Ellison syndrome and idiopathic hypersecretion
Composition
- Contains Esomeprazole MUPS 20 Tablet
- Contains Esomeprazole MUPS 40 Tablet
Dosage
- 40 mg once daily for adults (≥18 years) with erosive esophagitis
- 20 mg once daily for children & adolescents (12-18 years) with erosive esophagitis
- 20 mg twice daily for adults (≥18 years) for H. pylori eradication
Pharmacology
- Inhibits gastric acid by blocking the hydrogen-potassium adenosine triphosphatase enzyme system
- Effective for short-term treatment of gastric and duodenal ulcers
- Used in prevention and treatment of NSAID associated gastric ulcers
Administration
- Tablets should be swallowed whole with liquid
- Can be dispersed in half a glass of non-carbonated water if required
- Should not be chewed or crushed
Interaction
- Extensively metabolized in the liver by CYP2C19 and CYP3A4
- Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
- May potentially interfere with CYP2C19, the major metabolizing enzyme
Contraindications
- Contraindicated in patients with known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- Manufacturer advises caution as it is not known if Esomeprazole or its metabolites appear in human breast milk
Precautions & Warnings
- Should be used carefully if the patient has severe liver dysfunction and severe renal impairment
- May slightly increase the risk of hip, wrist and spine fracture
Storage Conditions
- Store in a cool & dry place below 25°C
- Protect from light
- Keep out of reach of children
Compounds
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image: Provided
Usability Features
- Ensures greater bioavailability
- Once daily dosing
- Uniform drug release
- Rapid and uniform gastric emptying
- Consistent and controlled pharmacological action
Design Elements
- MUPS abbreviation for Multiple-Unit Pellet System
Technical Specifications
- Esomeprazole Magnesium Trihydrate USP
Color Options
- Not Applicable
Dimensions
- Tablet size information not available
Materials
- Esomeprazole enteric coated pellets
Functions
- Reduces the amount of acid produced in the stomach
- Aids in healing erosive esophagitis
- Prevents erosive esophagitis recurrence
Drug Interactions
- No clinically significant interactions with phenytoin, warfarin, quinidine, clarithromycin or amoxicillin
Age Restrictions
- Not approved for use in children younger than 1 year
Additional Information
- EMT MUPS is abbreviation for Multiple-Unit Pellet System
FAQs
- Common Questions about EMT MUPS 20 mg Tablet provided