Osto-Coral 500 mg+200 IU (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Indications

  • Treatment & prevention of osteoporosis
  • Treatment & prevention of osteomalacia
  • Treatment & prevention of tetany
  • Treatment & prevention of hypoparathyroidism
  • Treatment & prevention of disorders of osteogenesis
  • Supplement for inadequate calcium intake in childhood diet
  • Supplement for inadequate calcium intake in pregnancy & lactation
  • Supplement for inadequate calcium intake in elderly patients
  • Treatment for pancreatitis
  • Phosphate binder in chronic renal failure

Composition

  • Each tablet contains Calcium Carbonate USP 1250 mg (Coral source)
  • Each tablet contains equivalent to 500 mg of elemental Calcium & Vitamin D USP 200 IU.
  • Each DX tablet contains Calcium Carbonate USP 1500 mg (Coral source)
  • Each DX tablet contains equivalent to 600 mg of elemental Calcium & Vitamin D USP 400 IU.
  • Each effervescent tablet contains Calcium Carbonate (Coral source) USP 1500 mg
  • Each effervescent tablet contains equivalent to 600 mg of elemental Calcium and Vitamin D3 400 IU as Cholecalciferol USP.

Pharmacology

  • Adequate Calcium in the blood is vital for bodily functions
  • Clinical evidence suggests usefulness for prevention and treatment of Osteoporosis and associated fractures
  • Vitamin D aids in Calcium absorption from GI tract
  • Vitamin D stimulates bone formation
  • Synergistic effects of Calcium and vitamin D on bone growth and in Osteoporosis prevention
  • Coral Calcium sourced from coral origin with similar composition to human bone
  • Vitamin D3 aids in absorption of Calcium from GI tract and helps maintain Calcium balance in the body.

Dosage & Administration

  • One tablet once or twice daily with plenty of water or as directed by the physician
  • Taking on a full stomach ensures better absorption
  • Dissolve 1 effervescent tablet in a glass of water to drink orally
  • Stir the solution with spoon before drinking
  • Taking on a full stomach ensures better absorption

Interaction

  • Thiazide diuretics reduce urinary excretion of calcium
  • Systemic corticosteroids reduce calcium absorption
  • Ion exchange resins and laxatives may reduce gastrointestinal absorption of vitamin D
  • Calcium carbonate may interfere with absorption of tetracycline preparations
  • Hypercalcaemia may increase toxicity of cardiac glycosides
  • Concurrent use with bisphosphonate or sodium fluoride may reduce gastrointestinal absorption
  • Oxalic acid and phytic acid may inhibit calcium absorption through formation of insoluble calcium salts

Contraindications

  • Hypercalcemia and hyperparathyroidism
  • Hypercalciuria and nephrolithiasis
  • Hypersensitivity to the components
  • Severe renal insufficiencies
  • Concomitant digoxin therapy

Side Effects

  • May be irritating to the GI tract
  • May cause constipation
  • Rarely produces hypercalcemia
  • May lead to allergic reactions, irregular heartbeats, nausea, vomiting, decreased appetite, dry mouth, drowsiness
  • Skin rash reported following vitamin D supplementation

Pregnancy & Lactation

  • Daily intake should not exceed 1500 mg calcium and 600 IU cholecalciferol
  • Reproductive toxicity shown in animals with high dose of vitamin D
  • Overdoses should be avoided as permanent hypercalcaemia has adverse effects on the foetus
  • No indications that vitamin D at therapeutic doses is teratogenic in humans
  • Calcium and vitamin D3 can be used during pregnancy and lactation

Precautions & Warnings

  • Serum calcium levels should be followed during long-term treatment
  • Renal function should be monitored through measurement of serum creatinine
  • Monitoring is especially important in elderly patients on concomitant treatment with cardiac glycosides or diuretics
  • Caution should be exercised in patients with high tendency to calculus formation
  • Vitamin D should be used with caution in patients with impairment of renal function
  • Soft tissue calcification risk should be taken into account
  • Vitamin D not metabolized normally in severe renal insufficiency

Overdose Effects

  • Can lead to hypervitaminosis D and hypercalcaemia
  • Symptoms may include anorexia, thirst, nausea, vomiting, constipation, abdominal pain, muscle weakness, fatigue, mental disturbances, polydipsia, polyuria, bone pain, nephrocalcinosis, nephrolithiasis, cardiac arrhythmias
  • Persistently high calcium levels may lead to irreversible renal damage and soft tissue calcification
  • Treatment options include discontinuation of calcium treatment, rehydration, and isolated or combined treatment with diuretics, bisphosphonates, calcitonin, and corticosteroids.

Therapeutic Class

  • Specific mineral & vitamin combined preparations

Storage Conditions

  • Store at temperature of below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Common Questions about Osto-Coral 500 mg Tablet

  • Combination of calcium carbonate and vitamin D3 for preventing and treating deficiency
  • Benefits include prevention and treatment of calcium and vitamin D deficiency, osteoporosis, rickets, osteomalacia, and improving bone health in the elderly
  • Contraindications include high level of calcium or vitamin D in the blood, kidney stones, sarcoidosis, and allergy to ingredients in Coralcal D
  • Side effects include constipation, nausea, vomiting, diarrhea, headache, drowsiness, and dry mouth
  • Dosage should be discussed with a doctor based on individual needs
  • Precautions include avoiding use in pregnancy or breastfeeding, high levels of calcium or vitamin D, kidney stones, and allergies to the medicine’s ingredients

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