Sulforid 4 mg (Tablet)
Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Glimepiride |
| Company | Desh pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise for Type II diabetes mellitus
- Combination therapy with metformin or insulin
- Control of hyperglycemia
- Usage in non-insulin dependent diabetes mellitus
- Additive effect with metformin
- Additive effect with insulin
- Potential for hypoglycemia
Pharmacology
- Sulfonylurea antidiabetic agent
- Decreases blood glucose concentration
- Stimulates insulin release from pancreatic beta cells
- Improves sensitivity of beta cells to glucose stimulus
- Reduction of basal hepatic glucose production
- Increased peripheral tissue sensitivity to insulin
- Long-lasting hypoglycemic action
Dosage
- Individualized based on desired blood sugar level
- Lowest effective dose
- Regular monitoring of glucose levels
- Initial dose of 1 mg once daily
- Gradual dose titration
- Usual dose range of 1 to 4 mg daily
- Timing and distribution determined by physician
- Secondary dosage adjustment based on improved diabetes control
- Changeover protocol from other oral antidiabetics
Administration
- Swallow with sufficient liquid
Interaction
- Potentiating interactions with ACE inhibitors, steroids, fluconazole
- Attenuating interactions with barbiturates, corticosteroids, diuretics
- Possible masking of hypoglycemic symptoms
- Unpredictable interaction with alcohol
Contraindications
- Not suitable for insulin-dependent diabetes mellitus
- Not for diabetic ketoacidosis or coma
- Hypersensitivity to sulfonylureas
- Severe hepatic or renal dysfunction
- Incompatible with dialysis
Side Effects
- Hypoglycemia
- Temporary visual impairment
- Gastrointestinal discomfort
- Urticaria
- Blood pressure changes
Pregnancy & Lactation
- Not to be taken during pregnancy
- Requirement for changeover to insulin
- Harmful during breastfeeding
Precautions & Warnings
- Initial weeks pose higher risk of hypoglycemia
- Careful monitoring needed
- Immediate intake of carbohydrates for hypoglycemia control
Overdose Effects
- Potential for hypoglycemic reactions
- Treatment with oral glucose
- Hospitalization for severe cases
Therapeutic Class
- Sulfonylureas
Storage Conditions
- Store below 30°C
- Keep away from light
- Keep out of reach of children