Vorimart 200 mg (Tablet)
Unit Price: ৳ 110.00 (1 x 10: ৳ 1,100.00)
Strip Price: ৳ 1,100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Desh pharmaceuticals ltd |
Category
- Antifungal Medicine
- Pharmaceuticals
- Medication
Indications
- Treatment of invasive aspergillosis
- Treatment of candidemia (nonneutropenic)
- Treatment of disseminated candidiasis in skin, abdomen, kidney, bladder wall, and wounds
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by Scedosporium apiospermum and Fusarium Species
- Treatment for patients intolerant of, or refractory to other therapy
Pharmacology
- Binds and inhibits ergosterol synthesis
- Inhibits CYP450-dependent 14-alpha sterol demethylase
- Results in depletion of ergosterol in fungal cell membrane
Dosage & Administration
- Oral administration with or without meals
- Different dosage regimens for patients above and below 40 kg body weight
- Loading dose regimen followed by maintenance dose
- Injection dosage for invasive aspergillosis, candidemia, Scedosporiosis, and Fusariosis
Interaction
- Adjust dosage and monitor for adverse reactions in the presence of CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
- Potential increase in concentrations and activity of drugs that are CYP3A4, CYP2C9, and CYP2C19 substrates
- Increase maintenance dosage with co-administration of specific drugs
Contraindications
- Known hypersensitivity to Voriconazole or any other components
- Co-administration contraindications with specific drugs
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- Use during pregnancy if the potential benefit justifies the potential risk to the fetus
Precautions & Warnings
- Careful assessment required for long term exposure greater than 180 days
- Reported association with squamous cell carcinoma of the skin (SCC) with long-term treatment
Use in Special Populations
- Efficacy not established in children under 12 years of age
Overdose Effects
- No data available for overdose effects
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Instructions for reconstituting suspension
- Shake the bottle well before adding water to loosen the powder
- Specific water volume and storage instructions provided
Storage Conditions
- Store in a dry place below 25°C temperature and protected from light
- Special storage requirement for Vorimart powder for suspension