Mygest 200 mg (Capsule)
Unit Price: ৳ 30.00 (3 x 10: ৳ 900.00)
Strip Price: ৳ 300.00
Medicine Details
Category | Details |
---|---|
Generic | Progesterone micronized capsule |
Company | Drug international ltd |
Also available as |
Indications
- Maintenance of Pregnancy in cases of Threatened / Recurrent abortion
- Luteal support during IUI and ART procedures IVF-ET
- Luteal support in cases of proven luteal phase insufficiency
- Along with estrogen in post-menopausal hormone replacement therapy (HRT)
- Prevent endometrial hyperplasia
- Progesterone challenge test in secondary amenorrhoea
- Cycle control along with estrogen therapy
- Dysfunctional uterine bleeding (DUB)
- Premenstrual tension
- Endometriosis
- Oocyte donation programme
- Benign mastopathy
Pharmacology
- Contains micronised progesterone
- Structurally and biologically identical to natural endogenous progesterone
- Increased bioavailability of progesterone with micronisation
- Metabolized to pregnanediols and pregnanolones in the liver
- Approximately 96%-99% bound to serum proteins
- Conjugates excreted in bile and urine
Dosage & Administration
- Usual recommended dose of Progesterone 100 mg/200 mg 2 to 3 soft gel capsules daily
- Flexible dosage regimen depending on the indication and patient's requirements
Interaction
- Inhibition of progesterone metabolism by ketoconazole
Contraindications
- Hypersensitivity
- Hepatic dysfunction
- Undiagnosed vaginal bleeding
- Porphyria
- Cancers of uterus and genital organs
- Breast cancers
- History of stroke or blood clots
Side Effects
- Devoid of estrogenic, androgenic and mineralocorticoid effects
- Reported side effects: mild somnolence, depression, breast tenderness, bloating
Precautions & Warnings
- Severe renal insufficiency
- Diabetes mellitus
- Seizures
- Migraine
- Headache
- Heart diseases
- Depression
Therapeutic Class
- Drugs for menopausal symptoms
- Hormone replacement therapy
- Female Sex hormones
- Oral Contraceptive preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children