Onbrez 300 mcg (Inhalation Capsule)

Unit Price: ৳ 126.50 (3 x 10: ৳ 3,795.00)
Strip Price: ৳ 1,265.00

Medicine Details

Category Details
Generic Indacaterol maleate
Company Novartis bangladesh ltd
Also available as
Onbrez 150 mcg inhalation capsule

Indications

  • Treatment of airflow obstruction in patients with COPD
  • Long-acting β2-adrenergic agonist
  • Maintenance bronchodilator treatment of airflow obstruction
  • Relaxation of bronchial smooth muscles

Description

  • Acts locally in the lung as a bronchodilator
  • Pharmacological effects include stimulation of intracellular adenyl cyclase
  • Once-daily maintenance bronchodilator treatment

Dosage & Administration

  • Once-daily inhalation of specified dosage
  • Oral inhalation only
  • No dosage adjustment for geriatric patients
  • Not indicated for pediatric population

Interaction

  • Interaction with Adrenergic Drugs, Xanthine Derivatives, Steroids, or Diuretics
  • Concomitant treatment with xanthine derivatives, steroids, or diuretics may potentiate hypokalemic effect
  • Administration with extreme caution to patients being treated with monoamine oxidase inhibitors, tricyclic antidepressants, or other drugs known to prolong the QTc interval
  • Interference with the effect of beta-blockers when administered concurrently

Contraindications

  • Contraindicated in patients with asthma without use of a long-term asthma control medication
  • Contraindicated in patients with a history of hypersensitivity to Indacaterol or to any of the ingredients

Side Effects

  • Commonly reported adverse effects: cough, nasopharyngitis, headache, nausea, oropharyngeal pain
  • Other reported effects: hypersensitivity reactions, paradoxical bronchospasm, tachycardia, pruritis, dizziness

Pregnancy & Lactation

  • Pregnancy Category C
  • Caution during pregnancy if potential benefit justifies potential risk to the fetus
  • Caution during nursing as active component may be excreted in human milk

Precautions & Warnings

  • Rarely, serious (sometimes fatal) breathing problems have happened to people with asthma using a long-acting inhaled beta agonist
  • Not shown to be safe or effective to treat asthma
  • Not approved for use in asthma

Overdose Effects

  • Signs and symptoms associated with over dosage: excessive beta-adrenergic stimulation, angina, hypertension or hypotension, tachycardia, arrhythmias, nervousness, headache, tremor, dry mouth, palpitation, muscle cramps
  • Risk of cardiac arrest and even death

Therapeutic Class

  • Long-acting selective β-adrenoceptor stimulants

Storage Conditions

  • Store in the blister, remove immediately before use
  • Keep in a cool & dry place
  • Keep out of the reach of children

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