Glipxen-M 2.5 mg+850 mg (Tablet)

Unit Price: ৳ 14.00 (4 x 7: ৳ 392.00)

Strip Price: ৳ 98.00

Medicine Details

Category	Details
Generic	Linagliptin metformin hydrochloride
Company	Beacon pharmaceuticals plc
Also available as	Glipxen m 25 mg tablet

Indications

Adjunct to diet and exercise
Improves glycemic control
Type 2 diabetes mellitus

Pharmacology

Inhibitor of DPP-4
Increases GLP-1 and GIP concentrations
Stimulates insulin release
Decreases glucagon secretion
Oral antihyperglycemic drug
Lowers plasma glucose
Decreases hepatic glucose production
Improves insulin sensitivity

Dosage & Administration

Immediate release tablet
Extended release tablet
Individualized dosage
Maximum recommended dose
Dose escalation
Starting dose recommendations

Interaction

Cationic drugs
Carbonic Anhydrase Inhibitors
Inducers of P-glycoprotein and CYP3A4 Enzymes
Drugs affecting glycemic control

Contraindications

Renal impairment
Metabolic acidosis
Hypersensitivity

Side Effects

Nasopharyngitis
Diarrhea
Hypoglycemia

Pregnancy & Lactation

Limited data in pregnant women
Caution during lactation

Precautions & Warnings

Discontinue in lactic acidosis
Discontinue in pancreatitis
Interactions with iodinated contrast
Monitor Vitamin B12 levels
Symptoms of lactic acidosis
Alcohol precautions
Other medicines precautions
Counseling recommendation
Travel precautions
Emergency preparedness
Hypoglycemia symptoms

Overdose Effects

Supportive measures
Hemodialysis or peritoneal dialysis unlikely for Linagliptin
Dialyzable Metformin Hydrochloride
No dose-related clinical adverse drug reactions for Linagliptin overdose
Hypoglycemia in Metformin Hydrochloride overdose
Lactic acidosis in Metformin Hydrochloride overdose

Therapeutic Class

Oral hypoglycemic preparations

Storage Conditions

Cool & dry place
Below 30°C
Protected from light & moisture
Keep out of reach of children

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