Rabepes 10 mg (Tablet (Enteric Coated))
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
Category | Details |
---|---|
Generic | Rabeprazole sodium |
Company | Beacon pharmaceuticals plc |
Also available as |
Indications
- Active duodenal ulcer
- Active benign gastric ulcer
- Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
- Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
- Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
- Zollinger-Ellison Syndrome
- In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease
Pharmacology
- Suppresses gastric acid secretion
- Inhibits the gastric H+/K+-ATPase
- Characterized as a gastric proton-pump inhibitor
Dosage
- 20 mg once daily in the morning for active duodenal ulcer and active benign gastric ulcer
- 20 mg once daily for four to eight weeks for erosive or ulcerative gastro-esophageal reflux disease (GERD)
- 10 mg once daily for symptomatic treatment of moderate to very severe GERD
- 60-120 mg once daily for Zollinger-Ellison Syndrome
Administration
Tablets should be taken in the morning, before eating, and swallowed whole
Interaction
- Potential interaction with drugs whose absorption is pH dependent
- Possible decrease in antifungal plasma levels when co-administered with ketoconazole or itraconazole
Contraindications
- Hypersensitivity to the active substance or excipients
- Contra-indicated in pregnancy and during breastfeeding
Side Effects
- Headache
- Diarrhea
- Abdominal pain
- Vomiting
- Constipation
- Dry mouth
- Increased or decreased appetite
- Muscle pain
- Drowsiness
- Dizziness
Pregnancy & Lactation
US FDA pregnancy category 'C', likely excreted in human milk
Precautions & Warnings
- Symptomatic response does not exclude presence of gastric or esophageal malignancy
- Regular surveillance for long-term treatment
- Possible modest increase in risk of hip, wrist, and spine fracture
- Risk of cross-hypersensitivity reactions with other proton pump inhibitors
- Potential for blood dyscrasias and hepatic enzyme abnormalities
Use in Special Populations
- No dosage adjustment necessary for patients with renal or hepatic impairment
- Not recommended for use in children
Overdose Effects
Representative of known adverse event profile, reversible without further medical intervention
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep below 30°C, away from light & moisture, out of the reach of children
Chemical Structure
- Molecular Formula: C18H21N3O3S
- Chemical Structure: Link to chemical structure image
Common Questions
- What is Rabepes 10 mg Tablet?
- What is it used for?
- What are the side effects?
- How should it be taken?
- Use during pregnancy or breastfeeding
- Overdose information
- Duration of treatment
- Other considerations like bone problems and vitamin D supplementation
- Quick Tips for usage
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