Rabepes 10 mg (Tablet (Enteric Coated))

Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00

Medicine Details

Indications

  • Active duodenal ulcer
  • Active benign gastric ulcer
  • Symptomatic erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Gastro-esophageal Reflux Disease Long-term Management (GERD Maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Zollinger-Ellison Syndrome
  • In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

  • Suppresses gastric acid secretion
  • Inhibits the gastric H+/K+-ATPase
  • Characterized as a gastric proton-pump inhibitor

Dosage

  • 20 mg once daily in the morning for active duodenal ulcer and active benign gastric ulcer
  • 20 mg once daily for four to eight weeks for erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • 10 mg once daily for symptomatic treatment of moderate to very severe GERD
  • 60-120 mg once daily for Zollinger-Ellison Syndrome

Administration

Tablets should be taken in the morning, before eating, and swallowed whole

Interaction

  • Potential interaction with drugs whose absorption is pH dependent
  • Possible decrease in antifungal plasma levels when co-administered with ketoconazole or itraconazole

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Contra-indicated in pregnancy and during breastfeeding

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Increased or decreased appetite
  • Muscle pain
  • Drowsiness
  • Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C', likely excreted in human milk

Precautions & Warnings

  • Symptomatic response does not exclude presence of gastric or esophageal malignancy
  • Regular surveillance for long-term treatment
  • Possible modest increase in risk of hip, wrist, and spine fracture
  • Risk of cross-hypersensitivity reactions with other proton pump inhibitors
  • Potential for blood dyscrasias and hepatic enzyme abnormalities

Use in Special Populations

  • No dosage adjustment necessary for patients with renal or hepatic impairment
  • Not recommended for use in children

Overdose Effects

Representative of known adverse event profile, reversible without further medical intervention

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep below 30°C, away from light & moisture, out of the reach of children

Chemical Structure

  • Molecular Formula: C18H21N3O3S
  • Chemical Structure: Link to chemical structure image

Common Questions

  • What is Rabepes 10 mg Tablet?
  • What is it used for?
  • What are the side effects?
  • How should it be taken?
  • Use during pregnancy or breastfeeding
  • Overdose information
  • Duration of treatment
  • Other considerations like bone problems and vitamin D supplementation
  • Quick Tips for usage

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