Heparest 3 gm/sachet (Oral Powder)

Indications

• Hepatic Encephalopathy
• Acute Liver Failure
• Hyperammonemia due to Acute and Chronic Hepatitis
• Fatty Liver
• Alcoholic Liver damage
• Adjunct to hepatotoxic drugs
• Liver Cirrhosis
• Post hepatitis convalescence

Pharmacology

• Combination of L-Ornithine and L-Aspartate
• Breaks down into L-Ornithine and L-Aspartate
• L-Ornithine converts toxic ammonia into non-toxic urea
• L-Aspartate an essential component of citric acid cycle
• Lowers the elevated level of ammonia in blood
• Assists in regeneration of damaged liver cells

Dosage

• Sachet
• Granules dissolved in water or juice
• Oral intake 3 times a day during or after meals
• Injection (Infusion Concentrate) up to 20 gm daily
• Up to 8 ampoules within 24 hours in severe conditions

Administration

• Can be added to conventional intravenous fluids
• Dilution rate of 1 ampoule per 100 ml of I.V. fluid
• Infusion rate: 5 gm/h at maximum
• Solution mixtures stable up to 24 hours

Interaction

• No data found regarding interactions

Side Effects

• Rarely nausea and vomiting occur
• Transient side effects
• Do not necessitate drug withdrawal

Pregnancy & Lactation

• Administration should be avoided

Precautions & Warnings

• Monitoring of serum and urinary urea levels

Therapeutic Class

• Digestive Enzyme

Storage Conditions

• Store in a cool and dry place
• Keep away from light

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