Venpa 25 mg (Capsule)

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Pregabalin
Company Maks drug limited
Also available as
Venpa 50 mg capsule Venpa 75 mg capsule

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues

Dosage

  • Maximum recommended dose of Pregabalin is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 ml/min
  • Recommended dose of Pregabalin is 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day) in patients with creatinine clearance of at least 60 ml/min
  • Recommended dose of Pregabalin for management of fibromyalgia in adults is 300 to 450 mg/day
  • Recommended dose range of Pregabalin for neuropathic pain associated with spinal cord injury in adults is 150 to 600 mg/day
  • Dosage should begin at 50 mg three times a day (150 mg/day) for diabetic peripheral neuropathy in adults

Administration

  • Route of administration: Oral route
  • Pregabalin CR tablet should be administered after an evening meal
  • When discontinuing both Pregabalin and Pregabalin CR, it should be gradually tapered over a minimum of 1 week

Interaction

  • Venpa is unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Most common side effects in adults are dizziness, somnolence, dry mouth, edema, blurred vision, weight gain and thinking abnormal
  • Most common side effects in pediatric patients for the treatment of partial onset seizures are increased weight and increased appetite

Pregnancy & Lactation

  • No adequate and well-controlled studies with pregabalin in pregnant women
  • Small amounts of pregabalin have been detected in the milk of lactating women

Precautions & Warnings

  • Angioedema can occur and may be associated with life threatening respiratory compromise requiring emergency treatment
  • Venpa should be withdrawn gradually over a minimum of 1 week
  • Venpa may cause peripheral edema
  • Caution should be exercised when coadministering Venpa and thiazolidinedione antidiabetic agents

Use in Special Populations

  • Safety and effectiveness in pediatric patients have not been established for the management of neuropathic pain
  • Safety and effectiveness of Venpa extended-release tablet in pediatric patients have not been established

Overdose Effects

  • Signs and symptoms are reduced consciousness, depression/anxiety, confusional state, agitation and restlessness
  • Seizures and heart block have also been reported
  • No specific antidote

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C), protected from light & moisture

Chemical Structure

  • Molecular Formula: C8H17NO2

Common Questions about Venpa 25 mg Capsule

  • Venpa 25 mg Capsule is an anticonvulsant and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia
  • Venpa 25 mg Capsule should be taken till the time you see an improvement in your health conditions
  • Venpa 25 mg Capsule should be taken after food in a prescribed dosage

Common Tips

  • Venpa 25 mg Capsule should be taken as per the dose and duration prescribed by your doctor
  • Venpa 25 mg Capsule may cause sleepiness. Do not drive or do anything requiring concentration until you know how it affects you
  • Venpa 25 mg Capsule may cause blurring or loss of vision. Inform your doctor immediately if you notice any vision changes

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