Ventus 5 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Escitalopram oxalate |
| Company | Maks drug limited |
| Also available as |
Indications
- Treatment of major depressive episodes
- Treatment of panic disorder with or without agoraphobia
- Treatment of social anxiety disorder (social phobia)
- Treatment of generalised anxiety disorder
- Treatment of obsessive-compulsive disorder
Pharmacology
- Selective serotonin reuptake inhibitor (SSRI)
- Pure S-enantiomer of the racemic bicyclic phthalate derivative citalopram
- At least 100 fold more potent than the R-enantiomer with respect to inhibition of 5-HT reuptake
- No or very low affinity for serotonergic or other receptors including alpha- and beta-adrenergic Dopamine, Histamine, Muscarinic and benzodiazepine receptors
Dosage
- Usual dosage is 10 mg once daily for major depressive episodes
- Initial dose of 5 mg is recommended for the first week for panic disorder
- Usual dosage is 10 mg once daily for social anxiety disorder
- Initial dosage is 10 mg once daily for generalised anxiety disorder
- Initial dosage is 10 mg once daily for obsessive-compulsive disorder
Administration
- Administered once daily, morning or evening
- May be taken with or without food
Interaction
- Should not be started until 2 weeks after stopping an MAOI
- An MAOI should not be started until at least a week after an SSRI or related antidepressant has been stopped
Contraindications
- Contraindicated in patients with known hypersensitivity to Escitalopram or Citalopram or any of the inactive ingredients of the drug product
- Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide is contraindicated
Side Effects
- Less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants
- Gastrointestinal effects include nausea, vomiting, dyspepsia, abdominal pain, diarrhoea, constipation
- Anorexia with weight loss, increased appetite and weight gain also reported
- Hypersensitivity reactions including rash, urticaria, angioedema, anaphylaxis, arthralgia, myalgia, and photosensitivity
- Other side-effects include dry mouth, nervousness, anxiety, headache, insomnia, tremor, dizziness, asthenia, hallucinations, drowsiness, convulsions, galactorrhoea, sexual dysfunction, urinary retention, sweating, hypomania or mania, movement disorders and dyskinesias, visual disturbances
Pregnancy & Lactation
- Excreted in human breast milk
- Physician should carefully consider the potential risks and benefits of treatment when treating a pregnant woman with Escitalopram during the third trimester
- Decision whether to continue or discontinue nursing or Escitalopram therapy should take into account the risk of citalopram exposure for the infant and the benefits Escitalopram treatment for the mother
Precautions & Warnings
- Used with caution in patients with epilepsy
- Avoid if poorly controlled, discontinue if convulsions develop
- Discontinue if convulsions develop
- History of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma
- Concomitant use of drugs that increase risk of bleeding
- Hepatic and renal impairment
Use in Special Populations
- Elderly patients (>65 years of age): Initial dosage is 5 mg once daily
- Ventus should not be used in the treatment of children and adolescents under the age of 18 years
- Dosage adjustment is not necessary in patients with mild or moderate renal impairment
- Caution and extra careful dose titration is advised in patients with severely reduced hepatic function
Overdose Effects
- Symptoms mainly related to the central nervous system, gastrointestinal system, and the cardiovascular system
- No specific antidote
- Establish and maintain an airway, ensure adequate oxygenation and respiratory function
- Gastric lavage and the use of activated charcoal should be considered
- Cardiac and vital signs monitoring are recommended
Therapeutic Class
- SSRIs & related anti-depressant drugs
Storage Conditions
- Store below 30°C temperature
- Protect from light & moisture
- Keep the medicine out of the reach of children