Ventus 10 mg (Tablet)
Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00
Medicine Details
Category | Details |
---|---|
Generic | Escitalopram oxalate |
Company | Maks drug limited |
Also available as |
Indications
- Treatment of major depressive episodes
- Treatment of panic disorder with or without agoraphobia
- Treatment of social anxiety disorder (social phobia)
- Treatment of generalised anxiety disorder
- Treatment of obsessive-compulsive disorder
Pharmacology
- Orally administered selective serotonin reuptake inhibitor (SSRI)
- Pure S-enantiomer of the racemic bicyclic phthalate derivative citalopram
- At least 100 fold more potent than the R-enantiomer with respect to inhibition of 5-HT reuptake
- No or very low affinity for serotonergic or other receptors including alpha- and beta-adrenergic Dopamine, Histamine, Muscarinic and benzodiazepine receptors
Dosage
- Usual dosage is 10 mg once daily for major depressive episodes
- Initial dose of 5 mg recommended for panic disorder before increasing to 10 mg daily
- Usual dosage is 10 mg once daily for social anxiety disorder
- Initial dosage is 10 mg once daily for generalised anxiety disorder
- Initial dosage is 10 mg once daily for obsessive-compulsive disorder
Administration
- Usually administered once daily, morning or evening with or without food
Interaction
- SSRI or related antidepressants should not be started until 2 weeks after stopping an MAOI
- Conversely, an MAOI should not be started until at least a week after an SSRI or related antidepressant has been stopped (2 weeks in the case of paroxetine and sertraline, at least 5 weeks in the case of fluoxetine)
Contraindications
- Contraindicated in patients with known hypersensitivity to Escitalopram or Citalopram or any of the inactive ingredients of the drug product
- Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide is contraindicated
Side Effects
- Less sedating and have fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants
- Side-effects of the SSRIs include gastrointestinal effects, anorexia with weight loss, hypersensitivity reactions, dry mouth, nervousness, anxiety, headache, insomnia, tremor, dizziness, asthenia, hallucinations, drowsiness, convulsions, galactorrhoea, sexual dysfunction, urinary retention, sweating, hypomania or mania, movement disorders and dyskinesias, visual disturbances
Pregnancy & Lactation
- Excreted in human breast milk
- The decision whether to continue or discontinue either nursing or Escitalopram therapy should take into account the risk of citalopram exposure for the infant and the benefits Escitalopram treatment for the mother
Precautions & Warnings
- Use with caution in patients with epilepsy
- History of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, concomitant use of drugs that increase risk of bleeding, history of bleeding disorders
- Hepatic and renal impairment
Use in Special Populations
- Initial dosage is 5 mg once daily for elderly patients (>65 years of age)
- Ventus should not be used in the treatment of children and adolescents under the age of 18 years
- Dosage adjustment is not necessary in patients with mild or moderate renal impairment
- Caution and extra careful dose titration is advised in patients with severely reduced hepatic function
Overdose Effects
- Symptoms seen in a reported overdose of escitalopram include symptoms mainly related to the central nervous system, the gastrointestinal system, and the cardiovascular system
- There is no specific antidote
- Establish and maintain an airway, ensure adequate oxygenation and respiratory function
Therapeutic Class
- SSRIs & related anti-depressant drugs
Storage Conditions
- Store below 30°C temperature and protect from light & moisture
- Keep the medicine out of the reach of children