Novas 500 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Maks drug limited |
Indications
- Relief of rheumatoid arthritis symptoms
- Relief of osteoarthritis symptoms
- Relief of ankylosing spondylitis symptoms
- Relief of juvenile arthritis symptoms
- Relief of tendonitis symptoms
- Relief of bursitis symptoms
- Relief of acute gout symptoms
- Management of primary dysmenorrhea & pain
Pharmacology
- Blocks COX-1 and COX-2 enzymes
- Decreases prostaglandin synthesis
- Offers antipyretic, analgesic, anti-inflammatory properties
Dosage & Administration
- Naproxen oral preparation intake with water
- Naproxen Enteric Coated Tablet dosage for adults and children
- Naproxen Suspension dosage for children over 2 years
- Naproxen Gel application frequency
Interaction
- Diminishes the antihypertensive effect of ACE inhibitors
- Delays the absorption of Novas by antacids & Sucralfate
- Increases adverse effects when taken with Aspirin
- Reduces the natriuretic effect of diuretics
- Enhances the toxicity of Methotrexate
- Increases the risk of GI bleeding when taken with Warfarin or Selective Serotonin Reuptake Inhibitors (SSRI)
Contraindications
- Known hypersensitivity to Naproxen
- Experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal side effects like heartburn, abdominal pain, nausea, diarrhea, dyspepsia
- Central Nervous System side effects like headache, vertigo, drowsiness
- Dermatological side effects like pruritus (itching), purpura
- Cardiovascular side effects like edema, palpitation
- Other side effects like visual disturbances, hearing disturbances
Pregnancy & Lactation
- Adverse effects on the fetus
- Causes a delay in parturition in animals
- Associated with premature closure of the ductus arteriosus and severe pulmonary hypertension in infants born to mothers taking Naproxen
- Excreted in small amounts in breast milk
- Balancing of benefits to the mother against the possible risks to the fetus required in the first and third trimesters
- Considered by some authorities to be too small to be harmful to a breast-fed infant
- Some manufacturers recommend that breastfeeding should be avoided during Naproxen therapy
Precautions & Warnings
- Risk of renal papillary necrosis and other abnormal renal pathology with long-term administration
- Reports of acute interstitial nephritis, hematuria, proteinuria and occasionally nephrotic syndrome associated with Novas-containing products
- Eliminated primarily by the kidneys
- Use with caution in patients with significantly impaired renal function
- Monitoring of serum creatinine and/or creatinine clearance advised in these patients
- Caution for patients with creatinine clearance of less than 20ml/min
- Reports of moderate to severe jaundice attributed to Novas
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children