Loterex 0.5% (Ophthalmic Gel)

5 gm tube: ৳ 200.00

Medicine Details

Category Details
Generic Loteprednol etabonate
Company Ibn sina pharmaceuticals ltd
Also available as
Loterex 05 suspension

Indications

  • Steroid responsive inflammatory conditions
  • Allergic conjunctivitis
  • Acne rosacea
  • Superficial punctate keratitis
  • Herpes zoster keratitis
  • Iritis
  • Cyclitis
  • Post-operative inflammation
  • Pain following ocular surgery

Pharmacology

  • Inhibition of inflammatory response
  • Delay or slow healing
  • Inhibition of edema
  • Fibrin deposition
  • Capillary dilation
  • Leukocyte migration
  • Capillary proliferation
  • Fibroblast proliferation
  • Deposition of collagen
  • Scar formation inhibition

Dosage and administration

  • Instill 1 drop into the conjunctival sac
  • Four times a day for 0.5% ophthalmic suspension
  • Two times a day for 1% ophthalmic suspension
  • Apply a small amount into conjunctival sac four times daily for ophthalmic ointment
  • Instill one to two drops into the conjunctival sac four times daily for ophthalmic gel
  • Use in children and geriatric use

Interaction

  • No impact on systemically administered medicinal products

Contraindications

  • Contraindicated in viral diseases of the cornea and conjunctiva
  • Mycobacterial infection of the eye
  • Fungal diseases of ocular structures
  • Known or suspected hypersensitivity to ingredients

Side effects

  • Elevated intraocular pressure
  • Optic nerve damage
  • Visual acuity and field defects
  • Cataract formation
  • Ocular infection
  • Perforation of the globe
  • Abnormal vision/blurring
  • Burning on instillation
  • Dry eyes
  • Itching
  • Photophobia
  • Non-ocular adverse reactions like headache, rhinitis, and pharyngitis

Pregnancy and lactation

  • Pregnancy Category C
  • Reproductive toxicity in animals
  • Caution in nursing women

Precautions and warnings

  • Re-evaluation if no improvement after two days
  • Monitor intraocular pressure if used for 10 days or longer
  • Consider fungus invasion in persistent corneal ulceration
  • Consult physician if redness or itching worsens
  • Avoid wearing contact lenses during therapy

Therapeutic class

  • Ophthalmic steroid preparations

Storage conditions

  • Store at below 30 degree C
  • Dry place protected from light
  • Do not touch tube tip to any surface
  • Do not use one month after first opening
  • Protect from freezing

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