Anzitor EZ 10 mg+10 mg (Tablet)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Atorvastatin ezetimibe
Company Square pharmaceuticals plc
Also available as
Anzitor ez 20 mg tablet

Indications

  • Reducing elevated total cholesterol
  • Lowering low-density lipoprotein cholesterol (LDL-C)
  • Increasing high-density lipoprotein cholesterol (HDL-C)
  • Reduction of elevated triglycerides (TG)
  • Adjunct to diet
  • Treatment for primary hyperlipidemia
  • Treatment for homozygous familial hypercholesterolemia (HoFH)

Pharmacology

  • Lowers plasma cholesterol
  • Inhibits HMG-CoA reductase
  • Reduces LDL production
  • Increases hepatic LDL receptors
  • Inhibits absorption of cholesterol by small intestine
  • Reduces blood cholesterol levels
  • Does not inhibit cholesterol synthesis in the liver

Dosage & Administration

  • Dosage range: 10/10 mg to 80/20 mg daily
  • Recommended starting dose: 10/10 mg or 20/10 mg daily
  • Administered as a single dose with or without food
  • Lipid levels analysis within 2 or more weeks post initiation
  • Dosage adjustment based on lipid levels

Interactions

  • Increased risk of myopathy with concurrent fibric acid derivatives
  • Enhanced risk of skeletal muscle effects with niacin
  • Monitoring required when coadministered with digoxin
  • Caution required when coadministered with colchicine or warfarin

Contraindications

  • Active liver disease
  • Hypersensitivity to any component of the preparation

Side Effects

  • Rhabdomyolysis
  • Myopathy
  • Abdominal pain
  • Increased hepatic enzymes

Pregnancy & Lactation

  • Contraindicated in pregnancy
  • Lipid-lowering drugs offer no benefit during pregnancy
  • Impact on long-term outcomes of primary hypercholesterolemia therapy is minimal if discontinued during pregnancy
  • Unknown excretion in human milk

Precautions & Warnings

  • Temporary withholding or discontinuation in case of myopathy
  • Liver enzyme tests prior to initiating therapy
  • Caution in case of liver injury or unexplained transaminase elevations
  • Exercise caution when administered with drugs decreasing endogenous steroid hormone levels

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No dosage adjustment necessary in geriatric patients

Overdose Effects

  • No specific recommended treatment
  • Symptomatic and supportive measures

Therapeutic Class

  • Other lipid regulating drugs

Storage Conditions

  • Do not store above 30°C
  • Keep in a dry place
  • Protect from light
  • Keep out of the reach of children

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