Vorifast 100 mg (Tablet)
Unit Price: ৳ 70.00 (1 x 10: ৳ 700.00)
Strip Price: ৳ 700.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Invasive aspergillosis
- Candidemia
- Disseminated candidiasis
- Esophageal candidiasis
- Scedosporium apiospermum infections
- Fusarium Species infections
- Refraction to other therapy
Pharmacology
- Triazole antifungal medication
- Inhibition of CYP450-dependent 14-alpha sterol demethylase
- Depletion of ergosterol in fungal cell membrane
Dosage & Administration
- Oral and Injection administration
- Loading and maintenance dose regimen based on body weight
- Different dosages for specific infections
Interaction
- CYP3A4, CYP2C9 and CYP2C19 inhibitors and inducers adjustment
- Potential increase in concentrations and activity of other drugs
- Interaction with Phenytoin and Efavirenz
Contraindications
- Hypersensitivity to Voriconazole or components
- Co-administration contraindications with specific drugs
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- Limited data in pregnant women
- Use during pregnancy based on benefit-risk balance
Precautions & Warnings
- Assessment of benefit-risk balance for long term exposure
- Reported association with squamous cell carcinoma of the skin (SCC)
Use in Special Populations
- Efficacy not established in children under 12 years of age
Overdose Effects
- Limited data available on overdose effects
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Instructions for reconstituting suspension
Storage Conditions
- Keep out of reach of children
- Store in a dry place and protected from light
- Storage temperature range for suspension