Adol Plus 500 mg+65 mg (Tablet)
Unit Price: ৳ 2.50 (12 x 10: ৳ 300.00)
Strip Price: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol caffeine |
| Company | Union pharmaceuticals ltd |
Indications
- Headache
- Migraine
- Toothache
- Neuralgia
- Feverishness
- Period pain
- Sore throat
- Backache
- Help to reduce the temperature
- Aches and pain of colds and flu
Pharmacology
- Combination of Paracetamol and Caffeine
- Analgesic and antipyretic properties of Paracetamol
- Weak anti-inflammatory activity of Paracetamol
- Caffeine as an alkaloid with theophylline-like xanthine derivative
- Caffeine increases the solubility and transmembrane permeation of Paracetamol
- Caffeine increases the pain threshold and tolerance of pain
- Caffeine raises vessel tone in the brain
Dosage & Administration
- Adult dose: 1-2 tablets every 4-6 hours
- Maximum adult dose: 8 tablets daily
- Child dose: Not recommended for children below 12 years
Interaction
- May reduce serum levels with anticonvulsants
- May enhance the anticoagulant effect of warfarin
- Accelerated absorption with metoclopramide and domperidone
- May increase serum levels with probenecid
- May increase serum levels of chloramphenicol
- May reduce absorption with colestyramine
- May cause severe hypothermia with phenothiazine
Contraindications
- Severe renal function impairment
- Hepatic disease (Viral Hepatitis)
- Known hypersensitivity to paracetamol or caffeine
Side Effects
- Mild side effects of paracetamol
- Haematological reactions including thrombocytopenia
- Leukopenia, pancytopenia, neutropenia, and agranulocytosis
- Pancreatitis
- Skin rashes
- Other allergic reactions
Pregnancy & Lactation
- Consultation required for pregnant mothers
- Safe while breastfeeding
Precautions & Warnings
- Cautious use in hepatic or renal failure patients
- Cautious use with other hepatotoxic medications
- Avoid prolonged use without consulting a physician
Overdose Effects
- Symptoms of Paracetamol overdose
- Liver damage may become apparent 12 to 40 hours after ingestion
- Abnormalities of glucose metabolism
- Metabolic acidosis
Therapeutic Class
- Non opioid analgesics
Storage Conditions
- Store in a cool and dry place
- Protect from light and moisture
- Keep all medicines out of the reach of children