Dolin 100 mg (Capsule)
Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Union pharmaceuticals ltd |
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Other infections
Description
- Highly active broad-spectrum antibiotic
- Effective against Gram-positive and Gram-negative bacteria
- Mechanism of action on protein synthesis
Pharmacology
- Semisynthetic tetracycline antibiotic
- Bacteriostatic antibiotic
- Active against Staphylococcus aureus and Nocardia
- Active against penicillin-resistant strains
- Sensitive to certain Gram-negative strains
- Active against Haemophilus influenzae
- Active against Nocardia, Chlamydia, Mycoplasma, and Rickettsiae
- Active against spirochetes
- Active against Plasmodium falciparum
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days
Administration
- Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing
Interaction
- Absorption impaired by antacid containing aluminium, calcium, or magnesium
- Absorption impaired by iron containing preparation
- Absorption impaired by bismuth salicylate
- Barbiturates, carbamazepine, and phenytoin decrease half-life of doxycycline
- Concurrent use with tetracyclines may render oral contraceptive less effective
- May require downward adjustment of anticoagulant dosages
- Tetracyclines should be avoided in conjunction with penicillin
Contraindications
- Hypersensitivity to any tetracyclines
- Children under 8 years of age
- Pregnant women
- Lactating mothers
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Skin rashes
- Hemolytic anaemia
- Eosinophilia
Pregnancy & Lactation
- Avoided in pregnant women due to risk of staining and effect on bone growth in the foetus
- Enters breast milk, mothers taking the drug should not breastfeed
Precautions & Warnings
- Avoid during tooth development in children under 8 years
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Store in cool and dry place
- Protected from light