Masil 200 mg (Capsule)
Unit Price: ৳ 25.00 (4 x 4: ৳ 400.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Union pharmaceuticals ltd |
Indications
- Treatment of Upper Respiratory Tract Infections (URTI)
- Treatment of Lower Respiratory Tract Infections
- Treatment of Urinary Tract Infections
- Effective against Streptococcus pneumonia
- Effective against Escherichia coli
- Highly stable in the presence of beta-lactamase enzymes
- Marked in-vitro bactericidal activity
- Clinical efficacy against commonly occurring pathogens
- Treatment of bronchitis
- Highly stable in the presence of Beta-lactamase enzyme
Pharmacology
- Third generation semisynthetic cephalosporin antibiotic
- Bactericidal against a broad spectrum of gram positive and gram negative bacteria
- Interferes in the synthesis of bacterial cell wall
- Highly stable in the presence of Beta-lactamase enzyme
- Approximately 40%-50% absorption rate
- Oral administration
Dosage & Administration
- Usual course of treatment is 7 days
- Recommended adult dosage is 200-400 mg daily
- Usual dosage for children is 8 mg/kg/day
- Dosage adjustment in severe renal impairment
- No established safety and efficacy in children aged less than 6 months
Interaction
- Increases in prothrombin times noted in a few patients
- Care required in patients receiving anticoagulant therapy
Contraindications
- Known hypersensitivity to cephalosporin antibiotics
Side Effects
- Common: Diarrhoea, nausea, abdominal pain, dyspepsia
- Less frequent: Headache, dizziness, pruritis, urticaria
- Infrequent: Thrombocytopenia, leukopenia, eosinophilia
- Mild transient change in liver and renal function tests
- Potential for Pseudomembraneous colitis
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Caution advised during pregnancy and lactation
Precautions & Warnings
- Caution in patients with hypersensitivity to other drugs
- Partial cross-allergenicity between penicillins and cephalosporins
- Caution in patients with markedly impaired renal function
- Altered normal flora of the colon, may permit overgrowth of clostridia
Overdose Effects
- Gastric Lavage may be indicated
- No specific antidote exists
- Not removed in significant quantities by dialysis
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of reach of children