Tase 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 6.00 (10 x 10: ৳ 600.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Union pharmaceuticals ltd |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect occurs within one hour
- Maximum effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
- Gradual return of secretory activity over 3 to 5 days upon discontinuation
Dosage
- Oral administration for various conditions and durations
- IV Injection for prophylaxis of acid aspiration, duodenal ulcer, gastric ulcer
- IV Infusion for intravenous administration over a period of 20-30 minutes
- Dosage regimen for pediatric use in severe ulcerating reflux esophagitis
Administration
- IV Injection for intravenous administration only
- IV Infusion over a period of 20-30 minutes or more
- Specific instructions for reconstitution, preparation, and usage of IV injection
- Caution on route of administration and compatibility with other drugs
Interaction
- Impact on absorption of ketoconazole
- Metabolism through cytochrome P450 affecting other drugs like diazepam, phenytoin, and warfarin
- Monitoring and potential dose adjustments for patients on warfarin or phenytoin
- No interaction with certain drugs and substances like phenacetin, alcohol, or food
- Increased plasma concentrations during concurrent administration with clarithromycin
Contraindications
- Hypersensitivity to omeprazole
- Potential delay in the diagnosis of malignancy in suspected gastric ulcer
Side Effects
- Mild and reversible adverse reactions
- Reported skin reactions, gastrointestinal reactions, neurological symptoms, and systemic effects
- Caution on severe reactions requiring discontinuation of therapy
Pregnancy & Lactation
- Results from prospective studies indicate no adverse effects on pregnancy or fetus
- Use during pregnancy with no known effects on the health of the fetus/newborn child
- No information available on passage into breast milk or effects on the neonate
- Discontinuation of breast-feeding if essential use of omeprazole is considered
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Potential association with increased risk for osteoporosis-related fractures
- Possible atrophic gastritis with long-term use
- Caution on concomitant use with methotrexate
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children