Ucard 5 mg (Tablet)
Unit Price: ৳ 3.50 (3 x 10: ৳ 105.00)
Strip Price: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Union pharmaceuticals ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Usage Category
- Monotherapy
- Combination therapy
Pharmacology
Dihydropyridine calcium-channel blocker
Duration of Action
Long
Treatment
- Hypertension
- Chronic stable angina pectoris
- Vasospastic angina
Dosage
- Hypertension:
- 5 mg once daily
- Max 10 mg once daily
- 2.5 mg for elderly patients with hepatic insufficiency
- Angina:
- 5-10 mg
- Lower dose for elderly and patients with hepatic insufficiency
- Most patients require 10 mg
- Administration: May be taken without regard to meals
Drug Interactions
- Potentially hazardous interactions: Avoid combination with p-blockers in patients with markedly impaired left ventricular function
- Other Significant Interactions:
- Digoxin
- Cimetidine
- Warfarin
- Food
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
Pregnancy Category C. Use only if benefit justifies potential risk to the fetus. Discontinue nursing while administered
Precautions & Warnings
- Hepatic impairment
- Pregnancy
- Breast feeding
Use in Special Populations
- Children with hypertension:
- 6-17 years of age
- 2.5 mg once daily as starting dose, up-titrated to 5 mg once daily if needed
- Children under 6 years old: Effect on blood pressure not known
- Elderly: Equally well tolerated at similar doses
- Renal impairment: Normal dosage recommended
- Hepatic impairment:
- Dosage recommendations not established in mild to moderate cases
- Lower dose initiation in severe cases
Overdose Effects
- Symptoms: Excessive peripheral vasodilatation, reflex tachycardia, systemic hypotension, shock
- Management:
- Active cardiovascular support
- Frequent monitoring of cardiac and respiratory function
- Elevation of extremities
- Attention to circulating fluid volume and urine output
- Use of vasoconstrictor
- Intravenous calcium gluconate may be beneficial
- Gastric lavage may be worthwhile in some cases
- Charcoal administration
- Dialysis unlikely to be beneficial due to high protein binding
Therapeutic Class
Calcium-channel blockers
Storage Conditions
Cool, dry place, protected from light