Uflu 500 mg (Capsule)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Flucloxacillin sodium |
| Company | Union pharmaceuticals ltd |
| Also available as |
Indications
- Skin and soft tissue infections
- Respiratory tract infections
- Osteomyelitis
- Enteritis
- Endocarditis
- Urinary tract infection
- Meningitis
- Septicaemia
- Prophylactic agent for major surgical procedures
Pharmacology
- Active against Gram-positive organisms including penicillinase producing strains
- Little activity against Gram-negative bacilli
- Inhibits the formation of bacteria cell wall
- Bactericidal antibiotic
- Interferes with peptidoglycan synthesis
- Resists the action of bacterial penicillinase
Dosage
- Oral administration for adults: 250 mg four times daily
- Oral administration for children (2-10 years): Half of adult dose
- Oral administration for children (Under 2 years): Quarter of adult dose
- Parenteral administration for adults: 250 mg four times daily
- Parenteral administration for children: Half of adult dose (2-10 years), Quarter of adult dose (Under 2 years)
Administration
Oral doses should be administered 1 hour before a meal
Interaction
Concurrent use with certain medications may result in increased levels of Uflu in the blood for a prolonged period
Contraindications
Contraindicated in penicillin hypersensitive patients
Side Effects
- Gastrointestinal tract issues (nausea, vomiting, diarrhea, etc.)
- Rashes
- Urticaria
- Purpura
- Fever
- Interstitial nephritis
- Hepatitis
- Cholestatic jaundice
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Caution advised during lactation
- No adequate and well-controlled studies in pregnant women
Precautions & Warnings
- Use with caution in patients with hepatic dysfunction
- Caution in the treatment of patients with an allergic diathesis
Use in Special Populations
In severe renal failure (creatinine clearance <10 ml/min), a reduction in dose or an extension of dose interval should be considered
Therapeutic Class
Penicillinase-resistant penicillins
Reconstitution
Used in other routes in conjunction with systemic therapy. Administered in intraarticular and intrapleural injections, inhaled by nebulizer
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children