Uride 850 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Union pharmaceuticals ltd |
Indications
- Treatment of type 2 diabetes mellitus in adults
- Treatment of type 2 diabetes mellitus in children and adolescents
- Reduction of diabetic complications in overweight type 2 diabetic adult patients
- Monotherapy for type 2 diabetes mellitus
- Combination therapy for type 2 diabetes mellitus
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Improves insulin sensitivity
- Decreases intestinal absorption of glucose
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Maximum recommended daily doses
- Usual starting dose for adults and children
- Dosage increases and maximum doses for immediate and extended-release tablets
- Dosage adjustments for renal impaired patients
Interaction
- Co-administration with Furosemide
- Potential interaction with Nifedipine
- Effect on cationic drugs eliminated by renal tubular secretion
- Effects on Cimetidine pharmacokinetics
- Drugs that may produce hyperglycemia and loss of glycemic control
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure (GFR <30 mL/min)
- Acute conditions altering renal function
- Conditions causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Peripheral neuropathy
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Risk of congenital abnormalities and perinatal mortality
- Excretion into human breast milk
- Adverse effects on breastfed newborns/infants
- Recommendation for insulin use during pregnancy
Precautions & Warnings
- Risk of lactic acidosis and vitamin B12 level
- Increased risk of hypoglycemia
- Monitoring of renal function
- Caution in conditions causing dehydration or trauma
- Interactions with other drugs
Use in Special Populations
- Adjusted dosage based on renal function in elderly subjects
- Diagnosis confirmation before treatment in pediatric population
- Caution in children aged between 10 and 12 years
- Renal function assessment and contraindications based on GFR
Overdose Effects
- Hypoglycemia and lactic acidosis
- Emergency treatment in hospital
- Hemodialysis for lactic acidosis
Therapeutic Class
- Biguanides
Storage Conditions
- Temperature below 30°C
- Protection from light and moisture
- Keep out of reach of children
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