Urodin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms
  • Staphylococci
  • Streptococci
  • Escherichia coli
  • Klebsiella spp
  • Proteus mirabilis
  • Haemophilus influenza
  • Shigella spp
  • Salmonella spp
  • Neisseria spp

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cell wall cross-linking process
  • Lysis of bacteria due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults
  • Oral administration for children
  • Oral administration for elderly
  • Injectable administration for adults
  • Injectable administration for children
  • Maximum daily dosage
  • Dosage adjustment in renal impairment

Interaction

  • Concomitant use of nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen, serum creatinine, alanine aminotransferase, aspartate aminotransferase, total bilirubin, alkaline phosphatase

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administered with care to patients hypersensitive to penicillins
  • Positive result in Coombs’ testing
  • False positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose
  • Caution in patients with rare hereditary problems

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Higher doses for chronic or severe infections
  • Additional monitoring for chronic urinary tract infections
  • Equivalent paediatric dosages
  • Transfer from intramuscular/intravenous to oral treatment

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Gastric lavage if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepare suspension
  • Reconstituted suspension shelf life
  • Injection solutions shelf life
  • Storage temperature impact on potency
  • Varied color of reconstituted solutions
  • Dispensing only on prescription of a registered physician

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