U-Tovas 10 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Union pharmaceuticals ltd

Title

U-Tovas 10 mg Tablet

Categories

  • Medicine
  • Health
  • Pharmacology

Description

U-Tovas is a selective inhibitor of HMG-CoA reductase, indicated for reducing elevated total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides levels in various diseases such as familial hypercholesterolaemia, mixed dyslipidemia, hypertriglyceridemia, and more. It is rapidly absorbed after oral administration and extensively metabolized by cytochrome P450 3A4. Atorvastatin is contraindicated during pregnancy and breastfeeding, and should be used with caution in patients with liver disease or renal dysfunction.

DosageAndAdministration

  • Adults: Usually 10 mg once daily; may be increased to max. 80 mg once daily
  • Child (10-18 years): Initially 10 mg once daily, increased if necessary to max. 20 mg once daily.

ModeOfAction

Atorvastatin is a selective inhibitor of HMG-CoA reductase, lowering plasma cholesterol and lipoprotein levels by inhibiting cholesterol synthesis in the liver and increasing the number of hepatic LDL receptors for enhanced uptake and catabolism of LDL.

Indications

  • Reducing total cholesterol and LDL cholesterol in familial hypercholesterolaemia
  • Treating patients with dyslipidemia and hypertriglyceridemia
  • Preventing cardiac ischaemic events in patients with coronary artery disease

Interaction

  • Concurrent administration with cyclosporine, fibric acid derivatives, niacin, erythromycin, or azole antifungals increases the risk of myopathy
  • Plasma concentrations may decrease with antacids and increase with erythromycin or oral contraceptives

Contraindications

  • Hypersensitivity to any component of the medication
  • Active liver disease or unexplained persistent elevations of serum transaminases

SideEffects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Headache
  • Back pain
  • Rash

PregnancyAndLactation

  • Contraindicated during pregnancy
  • Not known whether excreted in human milk

PrecautionsAndWarnings

  • Liver function tests should be performed before the initiation of treatment and periodically thereafter
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

UseInSpecialPopulations

  • Plasma concentrations are higher in healthy elderly subjects than in young adults
  • Renal disease has no influence on the plasma concentrations of U-Tovas
  • Hemodialysis is not expected to significantly enhance clearance of U-Tovas

OverdoseEffects

Specific treatment is not available for atorvastatin overdose; the patient should be treated symptomatically and supportive measures instituted, as required.

TherapeuticClass

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

StorageConditions

Keep in a dry place away from light and heat, and out of the reach of children.

ChemicalStructure

  • MolecularFormula: C33H35FN2O5
  • ChemicalStructureImageURL: https://medex.com.bd/storage/res/g-res-92-atorvastatin-calcium-chemical-structure-vKDE8RIA4syu8MLTgdLW.svg

CommonlyAskedQuestions

  • WhatIsIt: A selective inhibitor of HMG-CoA reductase used to avoid heart attacks and treat conditions such as Mixed Dyslipidemia and Hypertriglyceridemia
  • HowToTakeIt: It should be taken by mouth once daily, at the same time each day, with or without food
  • Uses: Treats diseases like Mixed Dyslipidemia and Hypertriglyceridemia, heart attacks, and Primary Hypercholesterolemia
  • SideEffectsList:
    • Cough
    • Muscle pain
    • Breathing difficulty
    • Running nose
  • StorageAndDisposalInstructions: Should be stored at room temperature, away from heat and direct light, and out of the reach of children and pets
  • DoesItLowerCholesterol: Yes, it is used to lower cholesterol and triglycerides present in the blood
  • RiskOfDiabetes: It can slightly affect blood sugar levels in type 2 diabetes patients
  • DurationOfUse: Should be taken for the duration prescribed by a doctor and considered safe for long-term use if taken as directed
  • CausesWeightLoss: No known reports of causing weight loss
  • IsItAPrescriptionForChildren: Should be used by adults, caution for children above 10 years old

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