Lovapres Plus 5 mg+40 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Nipro jmi pharma ltd |
| Also available as |
Indications
- Treatment of hypertension alone or with other antihypertensive agents
- Lowering blood pressure
- Initial therapy for patients likely to need multiple antihypertensive agents
- Individualized therapy based on baseline blood pressure and target goal
Pharmacology
- Amlodipine as dihydropyridine calcium channel blocker
- Greater effect on vascular smooth muscle cells than on cardiac muscle cells
- Peripheral arterial vasodilator
- Olmesartan Medoxomil as angiotensin II receptor antagonist
- Blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II
Dosage & Administration
- Initial therapy with 5/20 mg once daily
- Titration up to a maximum of 10/40 mg once daily
- Decreased clearance of Amlodipine among elderly patients
- Recommended starting dose of Amlodipine is 2.5 mg for patients 75 years and older
Interaction
- Potential attenuation of antihypertensive effect by NSAIDs including selective COX-2 inhibitors
Contraindications
- Not to be co-administered with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Intestinal problems known as sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Not to be used in 2nd and 3rd trimester
- Potential adverse effects on nursing infants
Precautions & Warnings
- Caution in volume- or salt-depleted patients
- Caution in patients with severe aortic stenosis
- Increased risk in patients with severe obstructive coronary artery disease
Use in Special Populations
- No established safety and effectiveness in pediatric patients
- No overall differences in safety or effectiveness in subjects aged 65 years and older
- No studies in patients with renal impairment
- Initial therapy not recommended in hepatically impaired patients
Overdose Effects
- No information available on overdose in humans
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children