Vorifix 50 mg (Tablet)
Unit Price: ৳ 35.00 (1 x 10: ৳ 350.00)
Strip Price: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Nipro jmi pharma ltd |
| Also available as |
Product Title
Categories
- Antifungal Medication
- Pharmaceutical Drug
- Medication
- Therapeutic Class: Antifungal Preparations
Description
Dimensions
Color Options
Functions
Materials
Technical Specifications
Design Elements
Usability Features
Age Group
- 12 years and older
Indications
- Invasive Aspergillosis
- Candidemia (nonneutropenic)
- Disseminated Candidiasis
- Esophageal Candidiasis
- Infections caused by Scedosporium apiospermum and Fusarium Species
- Patients intolerant of or refractory to other therapy
Pharmacology
- Triazole Antifungal Medication
- Binds and inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-alpha sterol demethylase
- Depletes ergosterol in fungal cell membrane
Dosage & Administration
- Oral tablet and powder for suspension
- Loading and maintenance dose based on body weight
- Injection dosing for different infections
Interaction
- Adjust dosage with CYP3A4, CYP2C9, and CYP2C19 inhibitors/inducers
- Potential drug interactions with CYP3A4, CYP2C9, and CYP2C19 substrates
- Increased maintenance dosage with Phenytoin or Efavirenz co-administration
Contraindications
- Hypersensitivity to Voriconazole or any other components
- Co-administration contraindications
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Careful assessment for long-term exposure
- Reported association with squamous cell carcinoma of the skin (SCC)
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No data found about overdose effects
Therapeutic Class
- Other Antifungal preparations
Reconstitution Instructions
- Shake the powder well before reconstitution
- Add specific amount of water and shake vigorously
- Store reconstituted suspension between 15°C-30°C
- Discard suspension 14 days after reconstitution
Storage Conditions
- Store in a dry place
- Keep out of reach of children
- Store powder for suspension between 2°C-8°C
- Protected from light