Vorifix 200 mg (Tablet)
Unit Price: ৳ 100.00 (1 x 10: ৳ 1,000.00)
Strip Price: ৳ 1,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Nipro jmi pharma ltd |
| Also available as |
Indications
- Invasive aspergillosis
- Candidemia
- Disseminated candidiasis
- Esophageal candidiasis
- Scedosporium apiospermum infections
- Fusarium species infections
- Treatment for refractory patients
Pharmacology
- Triazole antifungal medication
- Binds and inhibits ergosterol synthesis
- Inhibition of CYP450-dependent 14-alpha sterol demethylase
Dosage & Administration
- Oral administration
- Loading dose regimen based on body weight
- Maintenance dose based on body weight
- Injection for invasive aspergillosis and candidiasis
- Different dosage for different fungal infections
Interaction
- CYP3A4, CYP2C9, CYP2C19 inhibitors and inducers interaction
- Potential for increased concentrations and activity of other drugs
- Specific dosage adjustments with co-administration of certain drugs
Contraindications
- Known hypersensitivity
- Co-administration restrictions with specific drugs due to risk of adverse reactions or loss of efficacy
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- Limited data on pregnancy use
- Consider potential benefits vs. risks during pregnancy
Precautions & Warnings
- Long-term exposure evaluation
- Reported association with squamous cell carcinoma of the skin (SCC)
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No data available on overdose effects
Therapeutic Class
- Belongs to class of Other Antifungal preparations
Reconstitution
- Specific instructions for reconstitution of suspension
- Storage guidelines for reconstituted suspension
Storage Conditions
- Storage instructions for tablets and suspension