Exelon Patch 15 13.3 mg/24 hr (Transdermal Patch)
Unit Price: ৳ 223.27 (1 x 30: ৳ 6,698.10)
Medicine Details
| Category | Details |
|---|---|
| Generic | Rivastigmine tartrate |
| Company | Novartis bangladesh ltd |
| Also available as |
Indications
- Symptomatic treatment of mild to moderately severe Alzheimer's dementia
- Symptomatic treatment of mild to moderately severe dementia in patients with Idiopathic Parkinson's disease
Pharmacology
- Carbamate derivative
- Reversible binding with and inactivation of cholinesterase
- Increased concentration of acetylcholine at cholinergic synapses
- Relatively specific for brain acetylcholinesterase and butyrylcholinesterase
Dosage
- Capsule dosage instructions
- Transdermal patch dosage instructions
- Initial dose titration
- Maintenance dose
- Re-initiation of therapy
- Mild to moderate Alzheimer's Disease and Parkinson’s Disease Dementia dosage
- Severe Alzheimer’s Disease dosage
- Retitration after treatment interruption
Administration
- Twice daily administration with meals
Interaction
- Exaggeration of succinylcholine-type muscle relaxants effects
- Caution with anaesthetic agents
- Possible dose adjustments or temporary treatment cessation
- Incompatibility with other cholinomimetic substances
- Potential interference with anticholinergic medicinal products
- No pharmacokinetic interaction with specific drugs
Contraindications
- Hypersensitivity to the active substance or other carbamate derivatives
Side Effects
- Commonly reported gastrointestinal adverse reactions
- Susceptibility of female patients to gastrointestinal adverse reactions and weight loss
Pregnancy & Lactation
- Limited clinical data available
- Not recommended during pregnancy unless clearly necessary
- Excretion into milk
- Not recommended for breastfeeding women
Precautions & Warnings
- Caution in patients with specific conditions
- Monitoring body weight
- Caution in asthma or obstructive pulmonary disease
- Potential exacerbation of urinary obstruction and seizures
- Warnings for pregnant and lactating women
Use in Special Populations
- Increased exposure in moderate renal and mild to moderate hepatic impairment
- Dosing recommendations for individual tolerability
- Not recommended for use in children
Overdose Effects
- Lack of clinical signs in most cases
- Possible symptoms including nausea, vomiting, diarrhoea, hypertension, hallucinations, bradycardia, and syncope
- Recommended management and symptomatic treatment for adverse reactions
- Use of atropine in massive overdose cases
- Avoidance of rivastigmine administration for 24 hours in asymptomatic overdose
Therapeutic Class
- Drugs for Dementia
Storage Conditions
- Cool and dry storage
- Protection from light