Sandostatin LAR 10 mg/vial (Injection)

10 mg vial: ৳ 14,490.00

Medicine Details

Indications

  • Acromegaly
  • Carcinoid Tumors
  • Vasoactive Intestinal Peptide Tumors
  • Symptomatic treatment
  • Reduction of growth hormone levels
  • Reduction of IGF-I levels
  • Suppress diarrhea and flushing episodes

Pharmacology

  • Synthetic analogue of somatostatin
  • Suppression of growth hormone secretion
  • Suppression of LH response
  • Reduction of gastrin secretion
  • Reduction of insulin secretion
  • Reduction of glucagon secretion

Dosage & Administration

  • Intramuscular administration
  • Intravenous administration
  • Subcutaneous administration
  • Prophylaxis of complications following pancreatic surgery
  • Treatment for variceal haemorrhage in cirrhosis patients

Interaction

  • Dosage adjustment with concurrent therapy may be necessary
  • Interactions with calcium channel blockers
  • Interactions with oral hypoglycaemics
  • Interactions with beta-blockers
  • Interactions with diuretics

Contraindications

  • Hypersensitivity

Side Effects

  • Local pain at site of injection
  • Stinging at site of injection
  • Tingling at site of injection
  • Anorexia
  • Nausea
  • Vomiting
  • Abdominal pain
  • Bloating
  • Flatulence
  • Loose stools
  • Steatorrhoea
  • Hypoglycaemia
  • Hyperglycaemia
  • Hypothyroidism
  • Cardiac conduction abnormalities
  • Pancreatitis

Pregnancy & Lactation

  • Category B for pregnancy
  • No evidence of risk in later trimesters

Precautions & Warnings

  • Renal disease
  • Risk of gall bladder disease
  • Diabetes mellitus
  • Hypothyroidism
  • Monitor levels of vitamin B12 during long term therapy

Use in Special Populations

  • Dosage reduction in severe renal impairment requiring dialysis

Therapeutic Class

  • Growth hormone antagonist

Storage Conditions

  • Store at 2-8° C
  • Stable at room temperature for up to 14 days

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