Neoral 25 mg (Capsule)
Unit Price: ৳ 59.00 (10 x 5: ৳ 2,950.00)
Strip Price: ৳ 295.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cyclosporine oral |
| Company | Novartis bangladesh ltd |
| Also available as |
Title
- Sporium Neoral
Categories
- Medicine
- Immunosuppressant
Description
- Cyclosporine-based medication
- Used for solid organ transplantation, bone marrow transplantation, endogenous uveitis, nephrotic syndrome, rheumatoid arthritis, psoriasis, and atopic dermatitis
- Potent immunosuppressive agent
- Various dosage regimens for different indications
- Interacts with a wide range of drugs
- Contraindicated in hypersensitivity, kidney failure, uncontrolled hypertension, uncontrolled infection, and known malignancies
- Common side effects include renal dysfunction, hypertension, tremor, nausea, and hypertrichosis
- Not recommended during pregnancy and lactation
- Precautions for avoiding excess ultraviolet light exposure and monitoring for infections
- Storage conditions for oral solution
Color Options
- N/A
Dimensions
- N/A
Functions
- Immunosuppression
- Prolongs survival of transplanted organs
- Reversibly acts on lymphocytes
- Reduces risk of rejection in transplant patients
Materials
- Cyclosporine
- Excipients in Sandimmun Neoral
Dosage and Administration
- Specific dosage for solid organ transplantation, bone marrow transplantation, endogenous uveitis, nephrotic syndrome, rheumatoid arthritis, psoriasis, and atopic dermatitis
- Initial and maintenance doses for different indications
- Oral administration
Interactions
- Drugs that decrease Neoral levels (e.g., barbiturates, carbamazepine)
- Drugs that increase Neoral levels (e.g., macrolide antibiotics, ketoconazole)
- Relevant drug interactions with digoxin, colchicine, and HMG-CoA reductase inhibitors
Contraindications
- Hypersensitivity to ciclosporin or excipients
- Kidney failure except in nephrotic syndrome
- Uncontrolled hypertension
- Uncontrolled infection
- History of known or diagnosed malignancy
Side Effects
- Renal dysfunction
- Hypertension
- Tremor
- Nausea
- Hypertrichosis
- Anorexia
- Headache
- Gingival hyperplasia
- Hepatic dysfunction
- Muscle cramps
- Anaemia
Pregnancy and Lactation
- Not recommended during pregnancy
- Cyclosporine passes into breast milk
Precautions and Warnings
- Risk of developing lymphomas and other malignancies
- Avoid excess ultraviolet light exposure
- Therapeutic strategies for long-term immunosuppressive therapy
- Regular monitoring of renal function and blood pressure
- Enhanced risk of hyperkalaemia
- Caution in treating patients with hyperuricaemia
- Vaccination may be less effective during treatment
Overdose Effects
- Renal dysfunction
- Elimination by nonspecific measures
Therapeutic Class
- Immunosuppressant
- Vaccines
- Anti-sera & Immunoglobulin
Storage Conditions
- Usage within 2 months of opening
- Storage temperature: 15 to 30°C