Gabarol CR 330 mg (Tablet (Controlled Release))

Unit Price: ৳ 45.00 (2 x 10: ৳ 900.00)
Strip Price: ৳ 450.00

Medicine Details

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

Structural derivative of the inhibitory neurotransmitter GABA

Dosage

  • Maximum recommended dose of Pregabalin is 100 mg three times a day for DPN
  • Recommended dose of Pregabalin is 75 to 150 mg two times a day or 50 to 100 mg three times a day for PHN
  • Recommended dose of Pregabalin is 300 to 450 mg/day for fibromyalgia
  • Recommended dose range of Pregabalin is 150 to 600 mg/day for spinal cord injury

Administration

  • Route of administration: Oral
  • Special Administration Instructions: Swallowed whole after an evening meal

Drug Interaction

Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

Contraindicated in patients with known hypersensitivity to Pregabalin

Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Thinking abnormal

Pregnancy & Lactation

Potential risk to a fetus, not recommended during breastfeeding

Precautions & Warnings

  • Angioedema can occur and may be associated with life-threatening respiratory compromise
  • Discontinue immediately in case of hypersensitivity reactions
  • Increase the risk of suicidal thoughts or behavior
  • May cause dizziness and somnolence, impairing ability to drive or operate machinery
  • Withdraw gradually over a minimum of 1 week
  • May cause peripheral edema
  • Exercise caution when coadministering with thiazolidinedione antidiabetic agents

Use in Special Populations

  • Use in children and adolescents: Safety and effectiveness not established for various conditions

Overdose Effects

  • Reduced consciousness
  • Depression/anxiety
  • Confusional state
  • Agitation and restlessness
  • Seizures
  • Heart block

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

Cool & dry place (below 30°C), protected from light & moisture

Chemical Structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg

Commonly Asked Questions

  • First-line treatment for neurotic pain, shingles, seizures and fibromyalgia
  • Duration of use depends on health conditions
  • Dosage frequency should be as prescribed
  • Should be taken after food
  • Storage and disposal instructions
  • Works differently for different diseases
  • Consult doctor before stopping
  • Can be used together with Diazepam
  • May cause weight gain, consult a dietician
  • Quick tips for usage

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