Lamitrin ER 50 mg (Tablet (Extended Release))
Unit Price: ৳ 22.00 (3 x 10: ৳ 660.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Lamotrigine |
| Company | Aci limited |
| Also available as |
Indications
- Adjunctive therapy for partial-onset seizures
- Adjunctive therapy for primary generalized tonic-clonic seizures
- Adjunctive therapy for generalized seizures of Lennox-Gastaut syndrome
- Monotherapy for epilepsy in patients aged 16 years and older
- Treatment of bipolar disorder in patients aged 18 years and older
Description
- Phenyltriazine antiepileptic medication
- Used to treat certain types of epilepsy and bipolar disorder
- Controls epileptic seizures by inhibiting voltage-sensitive sodium channels
- Stabilizes neuronal membranes
- Inhibits presynaptic excitatory neurotransmitter release
Pharmacology
- Inhibits voltage-sensitive sodium channels
- Modulates release of excitatory neurotransmitters
- Binds to inactive sodium channels
- Suppresses release of glutamate
- Displays binding properties to various receptors
Dosage & Administration
- Escalation regimen for patients older than 12 years with epilepsy
- Escalation regimen for patients aged 2 to 12 years with epilepsy
- Escalation regimen for adults with bipolar disorder
- Initial weight-based dosing guide for patients aged 2 to 12 years taking Valproate
Interaction
- Increase in concentrations with Valproate
- Decrease in concentrations with Carbamazepine, Phenytoin, Phenobarbital, Primidone, Rifampin, estrogen-containing oral contraceptives, lopinavir/ritonavir, atazanavir/ritonavir
Side Effects
- Dizziness
- Headache
- Diplopia
- Nausea
- Blurred vision
- Somnolence
- Rash
- Vomiting (in children)
- Diarrhea (in children)
Pregnancy & Lactation
- Pregnancy Category C
- Excretion in human milk
- Potentially serious adverse reactions in nursing infants
- Consideration for discontinuing nursing or the drug
Precautions & Warnings
- Discontinue at first sign of rash
- Monitor for blood dyscrasias
- Monitor for suicidal behavior and ideation
- Monitor for signs of aseptic meningitis
Use in Special Populations
- Safety and effectiveness in very young pediatric patients
- Safety and effectiveness in pediatric patients for bipolar disorder
Overdose Effects
- Ataxia
- Nystagmus
- Seizures
- Decreased level of consciousness
- Coma
- Intraventricular conduction delay
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Keep out of reach of children
- Store in dry place
- Below 25°C temperature
- Protected from light