Exilant 30 mg (Capsule (Enteric Coated))

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Dexlansoprazole
Company Pharmasia limited
Also available as
Exilant 60 mg capsule

Title

  • Exilant Dexlansoprazole Delayed-Release Capsules

Categories

  • Proton Pump Inhibitor
  • Gastrointestinal Medication

Description

  • Exilant Dexlansoprazole Delayed-Release Capsules help in the healing of erosive esophagitis, maintenance of healed erosive esophagitis, relief of heartburn, and treatment of symptomatic non-erosive Gastroesophageal Reflux Disease (GERD). It is available as a Dual Delayed Release (DDR) formulation in a capsule for oral administration.

Dimensions

  • Capsule size: standard pharmaceutical capsule size

Color options

  • Not applicable

Functions

  • Healing of all grades of erosive esophagitis for up to 8 weeks
  • Maintenance of healed erosive esophagitis and relief of heartburn for up to 6 months
  • Treatment of heartburn associated with symptomatic non-erosive GERD for 4 weeks

Materials

  • Active ingredient: Dexlansoprazole
  • Capsule shell material: Not specified

Technical specifications

  • Proton Pump Inhibitor (PPI)
  • Suppression of gastric acid secretion by specific inhibition of the (H+/K+)-ATPase in the gastric parietal cell
  • Dual Delayed Release (DDR) formulation with two types of enteric-coated granules with different pH-dependent dissolution profiles

Design elements

  • Capsule formulation with enteric-coated granules
  • Dual delayed release for distinctive plasma concentration-time profile

Usability features

  • Can be taken without regard to food
  • Can be swallowed whole or administered by sprinkling intact granules on one tablespoon and then swallowing immediately

Dosage recommendations

  • Dexlansoprazole Capsules:
    • Healing of erosive esophagitis: 60 mg once daily for up to 8 weeks
    • Maintenance of healed erosive esophagitis and relief of heartburn: 30 mg once daily
    • Symptomatic Non-Erosive GERD: 30 mg once daily for 4 weeks
  • Dexlansoprazole MUPS:
    • Maintenance of healed erosive esophagitis and relief of heartburn: One 30 mg tablet once daily for 6 months in adults and 16 weeks in patients 12 to 17 years of age
    • Symptomatic Non-Erosive GERD: One 30 mg tablet once daily for 4 weeks

Administration methods

  • Swallowing the capsule whole
  • Oral administration by sprinkling intact granules on one tablespoon and then swallowing immediately

Interactions

  • With medicine:
    • Atazanavir
    • Warfarin
    • Tacrolimus
    • Clopidogrel
    • Methotrexate
  • With food & others:
    • No data available

Contraindications

  • Known hypersensitivity to any component of the formulation

Side effects

  • Diarrhea
  • Abdominal pain
  • Nausea
  • Vomiting
  • Flatulence

Pregnancy and lactation

  • Pregnancy Category B
  • No adequate and well-controlled studies with Dexlansoprazole in pregnant women or lactating mothers

Precautions and warnings

  • Gastric Malignancy
  • Clostridium difficile Associated Diarrhea
  • Bone fracture
  • Hypomagnesemia
  • Concomitant use of Exilant with Methotrexate

Special population use

  • Children & adolescents: Safety and effectiveness not established for patients below 12 years of age
  • Geriatric use: No dose adjustment necessary
  • Renal impairment: No dose adjustment necessary
  • Hepatic impairment: No dose adjustment necessary for mild hepatic impairment; consideration of a maximum daily dose of 30 mg for moderate hepatic impairment

Overdose effects

  • No reports of significant overdose
  • Multiple doses of 120 mg and a single dose of 300 mg did not result in severe adverse events

Therapeutic class

  • Proton Pump Inhibitor

Storage conditions

  • Store below 30°C and in a dry place
  • Protect from light
  • Keep out of reach of children

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