Exilant 60 mg (Capsule (Enteric Coated))

Unit Price: ৳ 17.00 (3 x 10: ৳ 510.00)
Strip Price: ৳ 170.00

Medicine Details

Category Details
Generic Dexlansoprazole
Company Pharmasia limited
Also available as
Exilant 30 mg capsule

Indications

  • Healing of Erosive Esophagitis
  • Maintenance of Healed Erosive Esophagitis
  • Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Pharmacology

  • Proton Pump Inhibitor
  • Suppression of Gastric Acid Secretion
  • Specific Inhibition of (H+/K+)-ATPase
  • R-enantiomer of Lansoprazole
  • Dual Delayed Release Formulation
  • Metabolism in the Liver
  • Excretion by Urine

Dosage

  • Dosing Recommendations for Dexlansoprazole
  • 30 mg Once Daily for Maintenance of Healed Erosive Esophagitis and Relief of Heartburn
  • 30 mg Once Daily for Symptomatic Non-Erosive Gastroesophageal Reflux Disease
  • 60 mg Once Daily for Healing of Erosive Esophagitis
  • 30 mg Once Daily for Maintenance of Healed Erosive Esophagitis and Relief of Heartburn for 6 Months (MUPS)
  • 30 mg Once Daily for Symptomatic Non-Erosive Gastroesophageal Reflux Disease (MUPS)

Administration

  • Can be Taken Without Regard to Food
  • Swallowed Whole
  • Granules Should Not Be Chewed
  • Option for Sprinkling Intact Granules

Interactions

  • Atazanavir
  • Warfarin
  • Tacrolimus
  • Clopidogrel
  • Methotrexate

Contraindications

  • Known Hypersensitivity to Any Component of the Formulation

Side Effects

  • Diarrhea
  • Abdominal Pain
  • Nausea
  • Vomiting
  • Flatulence

Pregnancy & Lactation

  • Pregnancy Category B
  • No Adequate and Well-Controlled Studies with Dexlansoprazole in Pregnant Women
  • No Adequate and Well-Controlled Studies with Dexlansoprazole in Lactating Mothers

Precautions & Warnings

  • Gastric Malignancy
  • Clostridium Difficile Associated Diarrhea
  • Bone Fracture
  • Hypomagnesemia
  • Concomitant Use with Methotrexate

Use in Special Populations

  • Safety and Effectiveness in Patients Below 12 Years Not Established
  • No Dose Adjustment Necessary for Elderly Patients
  • No Dose Adjustment Necessary for Patients with Renal Impairment
  • No Dose Adjustment Necessary for Patients with Mild Hepatic Impairment
  • Consider Maximum Daily Dose for Patients with Moderate Hepatic Impairment

Overdose Effects

  • No Reports of Significant Overdose of Exilant
  • Multiple Doses of Exilant 120 mg or Single Dose of Exilant 300 mg Did Not Result in Severe Adverse Events

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Store Below 30°C
  • Store in a Dry Place
  • Protected from Light
  • Keep Out of Reach of Children

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