Lexapro 10 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Escitalopram oxalate
Company Biopharma limited
Also available as

Title and Categories

  • Lexapro
  • Anti-depressant drug
  • SSRI
  • Selective serotonin reuptake inhibitor
  • Escitalopram

Indications

  • Treatment of major depressive episodes
  • Treatment of panic disorder with or without agoraphobia
  • Treatment of social anxiety disorder (social phobia)
  • Treatment of generalised anxiety disorder
  • Treatment of obsessive-compulsive disorder

Pharmacology

  • Orally administered
  • Pure S-enantiomer of racemic bicyclic phthalate derivative citalopram
  • At least 100 fold more potent than the R-enantiomer with respect to inhibition of 5-HT reuptake
  • No or very low affinity for serotonergic or other receptors including alpha- and beta-adrenergic Dopamine, Histamine, Muscarinic, and benzodiazepine receptors

Dosage

  • Safety of daily doses above 20 mg has not been demonstrated
  • May be taken with or without food
  • Individual patient response dependent dosage adjustments
  • Usual dosage for different conditions
  • Necessary time for obtaining antidepressant response
  • Long-term treatment for consolidation of response

Administration

  • Administered once daily
  • Morning or evening administration

Interaction

  • Time gaps between starting or stopping SSRI/related antidepressants and MAOIs
  • Time gaps for starting MAOI after stopping SSRIs
  • Time gaps for starting MAOI after stopping related antidepressant

Contraindications

  • Known hypersensitivity to Escitalopram or Citalopram or any of the inactive ingredients of the drug product
  • Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide

Side Effects

  • Less sedating and fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants
  • Range of gastrointestinal effects
  • Weight-related effects
  • Hypersensitivity reactions
  • Other common and less common side effects

Pregnancy & Lactation

  • Consideration of potential risks and benefits of treatment during the third trimester
  • Excretion in human breast milk
  • Need for careful decision-making in continuing or discontinuing nursing or Escitalopram therapy

Precautions & Warnings

  • Caution in patients with specific medical conditions
  • Use in patients with epilepsy, cardiac disease, diabetes mellitus, angle-closure glaucoma, bleeding disorders, hepatic and renal impairment
  • Advice on concurrent electroconvulsive therapy or history of mania

Use in Special Populations

  • Recommended dosages for elderly patients, children, and adolescents
  • Adjustment considerations for patients with reduced renal or hepatic function
  • Cautionary measures for poor metabolizers of CYP2C19

Overdose Effects

  • Symptoms related to the central nervous system, gastrointestinal system, cardiovascular system, and electrolyte/fluid balance conditions
  • Non-specific antidote
  • Recommendations for handling overdose situations

Therapeutic Class

  • SSRIs & related anti-depressant drugs

Storage Conditions

  • Store below 30°C temperature
  • Protection from light & moisture
  • Keep the medicine out of the reach of children

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