Vesidon 10 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | C2c pharma ltd |
Title
- Vesidon 10 mg Tablet
Categories
- Medicine
- Gastrointestinal Medication
- Prokinetic Drug
Description
- Dopamine antagonist for nausea and vomiting
- Increases gastric emptying
- Blocks dopamine receptors in Chemoreceptor Trigger Zone
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis
- Restores normal motility and tone of upper gastrointestinal tract
Color Options
- White
Dosage Form
- Tablet
- Suspension
- Paediatric drops
Dosage Instructions
- Take 15-30 minutes before meals
- Adults: 10-20 mg every 6-8 hours daily
- Maximum dose: 80 mg daily
- Children: 2-4 ml suspension/10 kg body weight every 6-8 hours daily
- Administer rectally in suppositories for adults
Indications
- Dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Blocks dopamine receptors in Chemoreceptor Trigger Zone and stomach
- Weak penetration across blood-brain barrier
Interaction
- Anticholinergic drugs antagonize antidyspeptic effect
- Antacids and antisecretory drugs lower oral bioavailability
- Metabolized through CYP3A4 pathway
- Examples of CYP3A4 inhibitors: azole antifungals, macrolide antibiotics, HIV protease inhibitors, nefazodone
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, obstruction, or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena in young children and adults
- Increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Use during first trimester if justified by therapeutic benefit
- Excretion in breast milk
- Not recommended for nursing mothers unless benefits outweigh potential risk
Precautions
- Use with caution in children due to risk of extra-pyramidal reactions
- Use with caution in patients with hepatic impairment
Special Population
- Use with caution in infants
- Use with caution in patients with liver or kidney disorders
Overdose Effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
Common Questions
- Used to treat nausea and vomiting
- Helps relieve nausea, vomiting, and indigestion
- May cause dizziness and sleepiness
- Avoid consuming alcohol when taking Vesidon 10 mg Tablet