Naushi 8 mg (Tablet)
Unit Price: ৳ 11.00 (2 x 10: ৳ 220.00)
Strip Price: ৳ 110.00
Medicine Details
Category | Details |
---|---|
Generic | Ondansetron |
Company | C2c pharma ltd |
Indications
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
- Prevention and treatment of post-operative nausea and vomiting
- Prevention of radiotherapy-induced nausea and vomiting
Description
- Orally dissolving film designed to be applied on top of the tongue
- Dissolves within 20 seconds and swallowed with saliva
- Does not require water to aid dissolution or swallowing
Pharmacology
- Highly selective 5HT3 receptor-antagonist
- Precise mode of action in control of nausea and vomiting is not known
- Blocks initiation of vomiting reflex by activating vagal afferents via 5HT3 receptors
Dosage
- Different dosages for adults, pediatric patients, radiotherapy-induced nausea and vomiting
- Oral solutions and oral soluble films available
Administration
- Step-by-step process for administration of oral soluble film
Interaction
- Additional data not available, no recommended dosage adjustment for patients on specific drugs
Contraindications
- Contraindicated in patients known to have hypersensitivity to the drug or any of its components
- Concomitant use of apomorphine
Side Effects
- Frequently reported adverse events: headache, constipation, diarrhea
- Rare cases of anaphylaxis, bronchospasm, tachycardia
- No evidence of extrapyramidal reactions
Pregnancy & Lactation
- No well-controlled studies in pregnant women
- Excreted in the breast milk of rats
Precautions & Warnings
- Hypersensitivity reactions reported in patients who have exhibited hypersensitivity to other selective 5-HT3 receptor antagonists
- Should not be used instead of nasogastric suction
- May mask a progressive ileus and/or gastric distension
Use in Special Populations
- Dosage recommendation similar for patients with impaired renal function
- Dosage adjustment recommended for patients with severe hepatic impairment
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Store at temperature not exceeding 30°C in a dry place
- Protect from light and moisture