Naushi 8 mg (Tablet)

Unit Price: ৳ 11.00 (2 x 10: ৳ 220.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Ondansetron
Company C2c pharma ltd

Indications

  • Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Description

  • Orally dissolving film designed to be applied on top of the tongue
  • Dissolves within 20 seconds and swallowed with saliva
  • Does not require water to aid dissolution or swallowing

Pharmacology

  • Highly selective 5HT3 receptor-antagonist
  • Precise mode of action in control of nausea and vomiting is not known
  • Blocks initiation of vomiting reflex by activating vagal afferents via 5HT3 receptors

Dosage

  • Different dosages for adults, pediatric patients, radiotherapy-induced nausea and vomiting
  • Oral solutions and oral soluble films available

Administration

  • Step-by-step process for administration of oral soluble film

Interaction

  • Additional data not available, no recommended dosage adjustment for patients on specific drugs

Contraindications

  • Contraindicated in patients known to have hypersensitivity to the drug or any of its components
  • Concomitant use of apomorphine

Side Effects

  • Frequently reported adverse events: headache, constipation, diarrhea
  • Rare cases of anaphylaxis, bronchospasm, tachycardia
  • No evidence of extrapyramidal reactions

Pregnancy & Lactation

  • No well-controlled studies in pregnant women
  • Excreted in the breast milk of rats

Precautions & Warnings

  • Hypersensitivity reactions reported in patients who have exhibited hypersensitivity to other selective 5-HT3 receptor antagonists
  • Should not be used instead of nasogastric suction
  • May mask a progressive ileus and/or gastric distension

Use in Special Populations

  • Dosage recommendation similar for patients with impaired renal function
  • Dosage adjustment recommended for patients with severe hepatic impairment

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Store at temperature not exceeding 30°C in a dry place
  • Protect from light and moisture

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