Libergy 10 mg (Tablet)

Indications

• Relief of symptoms associated with seasonal & perennial allergic rhinitis
• Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
• Treatment of allergen-induced asthma

Pharmacology

• Potent H1 receptor antagonist
• No significant anticholinergic and antiserotonic effects
• Inhibits histamine-mediated early phase of allergic reaction
• Reduces migration of inflammatory cells and release of mediators
• Peak plasma concentration achieved within one hour of administration
• Plasma half-life approximately 11 hours

Dosage & Administration

• Adult dosage: 1 tablet or 2 teaspoonfuls daily
• Children (6 years and older) dosage: 1 tablet or 1 teaspoonful twice daily
• Children (2-6 years) dosage: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
• Injectable dosage for adults and adolescents: 10 mg administered by intravenous injection

Interaction

• No clinically significant drug interactions with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin

Contraindications

• Contraindicated in patients with history of hypersensitivity to Cetirizine or hydroxyzine

Side Effects

• Common side effect: somnolence

Pregnancy & Lactation

• US FDA Pregnancy Category B
• Cetirizine excreted in human milk
• Caution advised when administered to nursing women

Precautions & Warnings

• Caution advised when driving or operating heavy machinery

Use in Special Populations

• Caution in patients with hepatic or renal insufficiency
• Safety demonstrated in pediatric patients aged 6 months to 5 years
• Clearance reduced in elderly patients

Therapeutic Class

• Sedating Antihistamine

Storage Conditions

• Keep in a dry place away from light and heat
• Keep out of the reach of children

Related Brands

• Cetirizine 10 mg (Tablet) - pristine-pharmaceuticals-ltd
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