Defcort 18 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anemia
- Idiopathic thrombocytopenic purpura
- Acute leukemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibits Phospholipase A2 enzyme
- Reduces release of certain immune system chemicals
Dosage & Administration
- Adult dosage range: 3-120 mg/day
- Maintenance doses: 3-18 mg/day
- Children dosage range: 0.25-1.5 mg/kg/day
- Alternate day administration for children
- Dose titration based on clinical need
Interaction
- Metabolized in the liver
- Recommendation for adjusting maintenance dose with liver enzyme inducers
- Recommendation for dose reduction with liver enzyme inhibitors
Contraindications
- Hypersensitivity to ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal issues
- Endocrine disturbances
- Neuropsychiatric effects
- Ophthalmic issues
- Fluid and electrolyte disturbances
- Increased susceptibility to infections
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Thromboembolism
Pregnancy & Lactation
- Corticosteroids crossing the placenta
- Risk of intrauterine growth retardation
- Excretion in breast milk
- Potential systemic effects in infants
Precautions & Warnings
- Special caution for cardiac disease or congestive heart failure
- Frequent patient monitoring
- Salt and water retention
- Increased excretion of potassium
- Special caution for gastritis or oesophagitis, diverticulitis, ulcerative colitis
- Dietary salt restriction and potassium supplementation
- Precautions for diabetes mellitus, osteoporosis, myasthenia gravis, renal insufficiency
- Special caution for emotional instability or psychotic tendency, epilepsy
- Precaution for liver failure, hypothyroidism, cirrhosis
- Ocular herpes simplex precautions
Use in Special Populations
- Dose monitoring for hepatic impairment
- No special precautions for renally impaired patients
- No special precautions for elderly patients
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Cool and dry storage below 25°C
- Protection from light and moisture
- Keep out of the reach of children