Esofour MUPS 20 mg (MUPS Tablet)
Unit Price: ৳ 9.00 (5 x 10: ৳ 450.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole mups preparation |
| Company | Albion laboratories limited |
Indications
- Gastro-esophageal Reflux Disease (GERD)
- Risk reduction in NSAID associated gastric ulcer
- H. pylori eradication (Triple therapy)
- Zollinger-Ellison syndrome and idiopathic hypersecretion
Composition
- Esomeprazole MUPS 20 Tablet: 20 mg Esomeprazole (as Esomeprazole Magnesium Trihydrate USP)
- Esomeprazole MUPS 40 Tablet: 40 mg Esomeprazole (as Esomeprazole Magnesium Trihydrate USP)
Description
- MUPS: Multiple-Unit Pellet System
- Ensures greater bioavailability
- Ensures uniform drug release
- Once daily dosing
- Combines fast acting and sustained action
Pharmacology
- Inhibits gastric acid by blocking the hydrogen-potassium adenosine triphosphatase enzyme system
Dosage
- Erosive esophagitis: 40 mg once daily for adults, 20 mg once daily for children & adolescents
- Maintenance of healing of erosive esophagitis: 20 mg once daily for adults and children & adolescents
- Risk reduction in NSAID associated gastric ulcer: 20 mg once daily for adults
- H. pylori eradication: 20 mg twice daily for adults and children & adolescents
- Zollinger-Ellison syndrome and idiopathic hypersecretion: 40-80 mg twice daily for adults
Administration
- Tablets should be swallowed whole with liquid
Interaction
- Extensively metabolized by CYP2C19 and CYP3A4
- No clinically relevant interactions with drugs metabolized by CYP enzymes
- Potential interference with CYP2C19
- May interfere with gastric pH-dependent drug absorption
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- Manufacturer advises caution
Precautions & Warnings
- Use carefully in severe liver dysfunction and severe renal impairment
- Slight increase in the risk of fractures
Storage Conditions
- Store in a cool & dry place below 25°C
- Protect from light
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
Common Questions
- PPIs work by reducing the amount of acid produced in the stomach
- Used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions
- Effectively prevents erosive esophagitis recurrence
- Common side effects like headaches, diarrhea, nausea, and gas
- Caution advised during pregnancy and breastfeeding
- Usually starts to work within a few hours of taking it