Freeway 200 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Al madina pharmaceuticals ltd |
| Also available as |
Title
Freeway Bronchodilator
Categories
- Medications
- Respiratory Health
- Bronchodilators
Description
Freeway is a medication used to treat bronchial asthma, bronchospasm, chronic obstructive pulmonary disease (COPD), and pulmonary disease with spastic bronchial component. It contains Doxophylline, a novel bronchodilator that selectively inhibits phosphodiesterase 4 and relaxes bronchial smooth muscle. The dosage varies for elderly, adults, and children above 12 years of age. Freeway should not be administered with other xanthine preparations and caution should be exercised in consuming caffeine. It is contraindicated in individuals with known hypersensitivity to the drug or other xanthine derivatives, as well as in patients with acute myocardial infarction, hypotension, and during lactation. Side effects may include nausea, vomiting, headache, and tachycardia. The use of Freeway during pregnancy and lactation should be carefully evaluated, and it does not affect the patient's alertness to drive or operate machinery. Special precautions should be taken for patients with cardiac disease, hypertension, and other specific conditions. In case of overdose, severe cardiac arrhythmias and tonic-clonic seizures may occur. Freeway belongs to the therapeutic class of bronchodilators and methyl xanthine derivatives, and should be stored in a dry place away from light and heat.
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Mode of Action
- Doxophylline selectively inhibits phosphodiesterase 4
- Relaxes bronchial smooth muscle
- Decreased affinities toward adenosine A1 and A2 receptors
Dosage and Administration
- Elderly: 200 mg tablet two or three times daily
- Adults: 400 mg tablet two or three times daily
- Children >12 years: 10 ml syrup or 200 mg tablet two or three times daily
- Children 6-12 years: 6-9 mg/kg body weight two times daily
- Doxophylline SR tablet to be taken once daily if required daily dose is 400 mg
Interaction
- Should not be administered with other xanthine preparations
- Caution with caffeine consumption
- Exercise caution with sympathomimetic drugs
- Concurrent administration with certain drugs may reduce hepatic clearance
- Phenytoin, other anticonvulsants, and cigarette smoking may increase clearance
Contraindications
- Known hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- During lactation
Side Effects
- Nausea
- Vomiting
- Headache
- Tachycardia
- Insomnia
- Hyperglycemia
- Albuminuria
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Pregnancy and Lactation
- Effects during pregnancy should be carefully evaluated case by case
- Contraindicated during lactation
- Does not interfere with the ability to drive or use machines
Precautions and Warnings
- Caution with factors that may reduce hepatic clearance
- Monitoring of blood levels recommended
- Caution in patients with specific conditions
- No risk of addiction or dependence
Overdose Effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
- Symptomatic treatment of cardiovascular collapse in case of overdose
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of reach of children
- Used only on prescription of specialist physician