G-Meropenem 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 500.00

Medicine Details

Title

  • G-Meropenem

Categories

  • Medicine
  • Antibiotic

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Bactericidal action by interfering with bacterial cell wall synthesis
  • Potent bactericidal activity against a broad spectrum of bacteria

Dosage

  • Administered intravenously every 8 hours
  • Dosage varies based on infection type and severity, and patient’s condition
  • Different dosages for adults and children
  • Dosage reduction for patients with renal impairment

Administration

  • Intravenous infusion over approximately 15-30 minutes
  • Intravenous bolus over approximately 3-5 minutes

Interaction

  • Competes with Probenecid for active tubular secretion
  • May reduce serum valproic acid levels

Contraindications

  • Hypersensitivity to G-Meropenem

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy category B
  • Caution during nursing

Precautions & Warnings

  • Discontinue if allergic reaction occurs
  • Use with careful monitoring in patients with hepatic disease

Use in Special Populations

  • Dosage adjustments for renal impairment
  • No dosage adjustments for hepatic impairment
  • Efficacy and tolerability in infants under 3 months not established

Overdose Effects

  • Rapid renal elimination in normal individuals
  • Haemodialysis in subjects with renal impairment

Therapeutic Class

  • Other beta-lactam Antibiotics

Reconstitution

  • Preparation for intravenous bolus and infusion administration
  • Compatible with various infusion fluids

Storage Conditions

  • Store in a cool, dry place
  • Keep away from light and moisture
  • Keep out of the reach of children

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