G-Vancomycin 1 gm/vial (IV Infusion)

1 gm vial: ৳ 200.00

Medicine Details

Title

G-Vancomycin

Categories

  • Antibiotics
  • Pharmacology
  • Therapeutic class

Description

G-Vancomycin is a potentially life-saving antibiotic used in the treatment of severe infections, including staphylococcal infections, endocarditis, pneumonia, and more. It binds tightly to bacterial cell wall precursors, inhibiting cell wall synthesis. The dosage and administration guidelines vary based on the patient's renal function, and the medication comes with precautions and warnings for renal function tests, injection site necrosis, and potential superinfection.

Indications

  • Potentially life-threatening infections
  • Severe staphylococcal infections
  • Endocarditis treatment
  • Surgical prophylaxis
  • Osteomyelitis
  • Pneumonia
  • Septicemia
  • Soft tissue infections

Pharmacology

  • Binds tightly to cell wall precursors
  • Inhibits cell wall synthesis
  • Damages cytoplasmic membrane

Dosage & Administration

  • Concentrations of 5 mg/ml or less
  • Rates of 10 mg/min or less in adults
  • Varied dosages based on renal function
  • Fluid restriction considerations
  • Capsule dosage for specific infections

Contraindications

  • Hypersensitivity to Vancomycin

Side Effects

  • Anaphylactic reactions
  • Hypotension
  • Wheezing
  • Flushing
  • Muscle spasm
  • Injection site complications

Pregnancy & Lactation

  • Caution during pregnancy
  • Excretion in human milk
  • Limited absorption by nursing infants

Precautions & Warnings

  • Serial auditory function tests
  • Periodic haematological studies
  • Tissue irritation
  • Injection site necrosis
  • Superinfection risk
  • Pseudomembranous colitis potential

Overdose Effects

  • Supportive care
  • Poor removal by dialysis
  • Limited benefit of haemoperfusion

Therapeutic Class

  • Other antibiotic

Storage Conditions

  • Cool and dry storage
  • Protection from light

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