G-Adrenaline 1 mg/ml (Injection)

1 ml ampoule: ৳ 20.00 (1 x 5: ৳ 100.00)

Medicine Details

Category Details
Generic Adrenaline
Company Gonoshasthaya pharma ltd

Indications

  • Management of cardiac arrest
  • Cardiopulmonary resuscitation
  • Allergic and anaphylactic reactions
  • Life threatening asthma

Description

  • Direct-acting sympathomimetic agent
  • Exerts effect on alpha and beta-adrenoceptors
  • Increases blood pressure
  • Increases heart rate
  • Rapid onset and short duration
  • Rapid metabolism in the liver and tissues

Pharmacology

  • Stimulation of adrenergic nerves
  • Acts on alpha and beta receptor sites
  • Produces rapid rise in blood pressure
  • Constricts arterioles in the circulation

Dosage & Administration

  • Intravenous injection
  • Endotracheal administration
  • Intracardiac puncture
  • Intraspinal administration
  • Dosage for adults and children
  • Dilution of adrenaline

Interaction

  • Excessive doses of digitalis
  • Mercurial diuretics
  • Sensitization of the heart to arrhythmias
  • Potentiation by tricyclic antidepressants
  • Potentiation by certain antihistamines
  • Potentiation by L-thyroxine Sodium

Contraindications

  • Hypertension
  • Arteriosclerosis
  • Coronary disease
  • Hyperthyroidism
  • Use with monoamine oxidase inhibitors

Side Effects

  • Anxiety
  • Restlessness
  • Dizziness
  • Headache
  • Palpitations
  • Weakness

Pregnancy & Lactation

  • Pregnancy Category C
  • Crosses the placenta
  • Excreted in breast milk
  • Caution in pregnancy
  • Not recommended during lactation

Precautions & Warnings

  • Solution appearance and stability
  • Sensitivity to alkalies and oxidizing agents
  • Caution with elderly patients
  • Use with caution in patients with specific conditions

Overdose Effects

  • Cardiac arrhythmia
  • Severe hypertension
  • Counteracting agents
  • Immediate resuscitation support

Therapeutic Class

  • Anaphylaxis
  • Mydriatic and Cycloplegic agents
  • Other adrenoceptor stimulants
  • Respiratory stimulants

Storage Conditions

  • Store below 25°C
  • Protect from light
  • Keep out of the reach of children

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