G-Daclatasvir 60 mg (Tablet)
Unit Price: ৳ 200.00 (1 x 10: ৳ 2,000.00)
Strip Price: ৳ 2,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Daclatasvir |
| Company | Gonoshasthaya pharma ltd |
Indications
- Treatment of chronic hepatitis C virus (HCV) infection in adults
Pharmacology
- Direct acting antiviral agent against the Hepatitis C Virus (HCV)
- Inhibitor of NS5A protein
- Binds to the N-terminus of NS5A
- Inhibits viral RNA replication and virion assembly
Dosage & Administration
- Recommended dose of 60 mg once daily
- Oral administration with or without meals
- Must be administered in combination with other medicinal products
- Available regimens and treatment duration for different patient groups
Interaction
- Substrate of CYP3A
- Moderate or strong inducers of CYP3A may affect plasma levels
- Inhibitor of P-glycoprotein transporter and organic anion transporting polypeptide
Contraindications
- Contraindicated in combination with drugs that strongly induce CYP3A
- Includes anticonvulsants, antimycobacterial agents, herbal products like St. John's wort
Side Effects
- Serious symptomatic bradycardia when coadministered with Sofosbuvir and Amiodarone
- Symptoms include fainting, dizziness, weakness, chest pain, confusion
Pregnancy & Lactation
- No data available for pregnant women or breastfeeding
Precautions & Warnings
- Risk of adverse reactions or loss of virologic response due to drug interactions
- Possible drug interaction outcomes
- Cases of symptomatic bradycardia with coadministration of Amiodarone and Sofosbuvir
Use in Special Populations
- No dose adjustment required for elderly, renal impairment, or hepatic impairment
- Safety and efficacy not established in children and adolescents
Overdose Effects
- No known antidote for overdose
- Treatment consists of general supportive measures
- Dialysis unlikely to significantly reduce plasma concentrations
Therapeutic Class
- Hepatic viral infections (Hepatitis C)
Storage Conditions
- Store at room temperature below 30°C
- Protect from light
- Keep out of the reach of children